{"id":"W2154016364","doi":"10.1128/aac.01547-05","title":"Mechanism of Enhanced Activity of Liposome-Entrapped Aminoglycosides against Resistant Strains of <i>Pseudomonas aeruginosa</i>","year":2006,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"Northeast Cancer Centre; Laurentian University","funders":"","keywords":"Liposome; Pseudomonas aeruginosa; Microbiology; Antibiotics; Bacteria; Bacterial outer membrane; Membrane permeability; Biology; Antibacterial agent; Flow cytometry; Chemistry; Membrane; Biochemistry; Molecular biology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002313725,0.0003944372,0.0003893863,0.0001311598,0.00008223906,0.0002942934,0.0002641036,0.0003930269,0.0005530358],"category_scores_gemma":[0.0001912954,0.0001417472,0.0002564538,0.00007203172,0.0002559881,0.0002924817,0.0002069056,0.0002981227,0.0002713214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003679554,"about_ca_system_score_gemma":0.0001335459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004018047,"about_ca_topic_score_gemma":0.0002464901,"domain_scores_codex":[0.9998494,0.0000502152,0.00001178271,0.00002248278,0.00003185501,0.00003420293],"domain_scores_gemma":[0.9999092,0.00002880122,0.00002913975,0.000007162002,0.00001627236,0.000009462935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009111172,0.00001443499,0.0001093691,0.00006499029,0.000004483119,0.00005029911,0.00001164366,0.00007744397,0.9984561,0.00008284527,0.00002566933,0.001011681],"study_design_scores_gemma":[0.00002259902,0.0003692753,0.002124328,0.000009470632,0.00001729798,0.0002442606,0.00001410469,0.0009435639,0.9954264,0.00002732151,0.0007961617,0.000005387795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884502,0.005593884,0.004288027,0.0001443241,0.00002967978,0.00009152554,0.0001985009,0.0001062714,0.001097588],"genre_scores_gemma":[0.9957626,0.001304096,0.002055828,0.00007175492,0.00000678252,0.00005960503,0.00009749179,0.00001031546,0.0006314713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005530358,"threshold_uncertainty_score":0.002669692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006497309651913539,"score_gpt":0.2231626552062845,"score_spread":0.216665345554371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}