{"id":"W2154047770","doi":"10.1155/2012/736532","title":"Double-Blinded, Vehicle-Controlled Proof of Concept Study to Investigate the Recurrence of Inflammatory and Noninflammatory Acne Lesions Using Tretinoin Gel (Microsphere) 0.04% in Male Patients after Oral Isotretinoin Use","year":2012,"lang":"en","type":"article","venue":"Dermatology Research and Practice","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Dermatrials Research","funders":"Johnson and Johnson","keywords":"Medicine; Isotretinoin; Acne; Tolerability; Tretinoin; Dermatology; Clinical endpoint; Randomized controlled trial; Lesion; Target lesion; Population; Surgery; Adverse effect; Internal medicine; Retinoic acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003480091,0.001221782,0.003058561,0.0003400926,0.0005594093,0.0006632806,0.0008427411,0.001394684,0.004039587],"category_scores_gemma":[0.001489389,0.0004707522,0.0008749694,0.0003172268,0.0009799663,0.000751456,0.0003066302,0.001619164,0.0005755106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003030017,"about_ca_system_score_gemma":0.001284911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002256604,"about_ca_topic_score_gemma":0.0007130346,"domain_scores_codex":[0.9987967,0.0005404857,0.0001241071,0.0002343527,0.0001729651,0.000131388],"domain_scores_gemma":[0.9987839,0.0002529627,0.0004173347,0.0001060429,0.0001752469,0.0002645256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7471179,0.1051057,0.001384227,0.002645314,0.0009051702,0.0001459753,0.000208806,0.0002908117,0.09740334,0.0001910042,0.001130933,0.0434708],"study_design_scores_gemma":[0.2730386,0.7148753,0.004025921,0.00003676743,0.000382536,0.00009539012,0.00004718047,0.0003433446,0.005866909,0.000062381,0.001209246,0.00001649586],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811035,0.002378325,0.002429642,0.0002632484,0.0005532284,0.01181371,0.0006190031,0.0001063368,0.0007330672],"genre_scores_gemma":[0.9692234,0.001808939,0.008367359,0.0005884927,0.0006781971,0.01608841,0.0004638493,0.00002393796,0.0027574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004039587,"threshold_uncertainty_score":0.01840472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1070632426841814,"score_gpt":0.3965093234533629,"score_spread":0.2894460807691814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}