{"id":"W2154098873","doi":"10.1128/iai.00533-13","title":"Requirement and Redundancy of the Src Family Kinases Fyn and Lyn in Perforin-Dependent Killing of Cryptococcus neoformans by NK Cells","year":2013,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; University of Calgary","keywords":"LYN; Biology; Src family kinase; Perforin; FYN; Cryptococcus neoformans; Cell biology; Kinase; Proto-oncogene tyrosine-protein kinase Src; Tyrosine-protein kinase CSK; Immunology; SH3 domain; Microbiology; CD8; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000197091,0.0003255624,0.0002947204,0.0001824047,0.0001519177,0.0003007915,0.0002823225,0.0002878837,0.0006274299],"category_scores_gemma":[0.0002414146,0.0002149011,0.0002796921,0.00009939299,0.0002527196,0.0002851888,0.0002870034,0.0003992021,0.0003372724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003587549,"about_ca_system_score_gemma":0.000397684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005721604,"about_ca_topic_score_gemma":0.0007618701,"domain_scores_codex":[0.9997657,0.00003719434,0.00003545661,0.00004290156,0.00005675874,0.00006190882],"domain_scores_gemma":[0.9998166,0.00003215611,0.00004894003,0.00002889608,0.00001971621,0.00005373321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007912978,0.00001099934,0.0002579651,0.00002129051,0.000002383483,0.00009594137,0.000006993364,0.00004878565,0.9988558,0.00008388729,0.000009260806,0.0005274989],"study_design_scores_gemma":[0.00006643411,0.0003364728,0.02861753,0.000009723182,0.00004813074,0.002361142,0.00007206795,0.003606043,0.963318,0.0001500626,0.001403203,0.00001120056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976876,0.0008380512,0.0007912389,0.00005854059,0.000007686387,0.000007372917,0.00007951709,0.00001608723,0.000513876],"genre_scores_gemma":[0.9979934,0.0002849415,0.0009103519,0.00002274224,0.000005052114,0.00001475958,0.0002379827,0.000004026748,0.0005269275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006274299,"threshold_uncertainty_score":0.002602994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01587110755572374,"score_gpt":0.247555400221206,"score_spread":0.2316842926654822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}