{"id":"W2154098873","doi":"10.1128/iai.00533-13","title":"Requirement and Redundancy of the Src Family Kinases Fyn and Lyn in Perforin-Dependent Killing of Cryptococcus neoformans by NK Cells","year":2013,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; University of Calgary","keywords":"LYN; Biology; Src family kinase; Perforin; FYN; Cryptococcus neoformans; Cell biology; Kinase; Proto-oncogene tyrosine-protein kinase Src; Tyrosine-protein kinase CSK; Immunology; SH3 domain; Microbiology; CD8; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001863928,0.00008775559,0.0001881481,0.00007024555,0.0001655831,0.00001249909,0.00001828847,0.00004563953,0.00002740107],"category_scores_gemma":[0.00003481223,0.00006043512,0.00002928672,0.0001072178,0.0001509781,0.0001083397,0.00007658049,0.0001612211,7.057548e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002649324,"about_ca_system_score_gemma":0.0000146652,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007506754,"about_ca_topic_score_gemma":0.0001345387,"domain_scores_codex":[0.9994444,0.00005006824,0.0002343027,0.00008728397,0.00008272292,0.0001011849],"domain_scores_gemma":[0.9996201,0.00004783214,0.00008272276,0.0001302503,0.00008642562,0.0000327092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004085276,0.0002841485,0.6151044,0.0003529541,0.00005717062,2.797154e-7,0.001269847,0.000008626352,0.3723552,0.0000984413,0.0003721377,0.01005593],"study_design_scores_gemma":[0.0009430011,0.0005117045,0.9359496,0.0002328172,0.00004047455,0.000010896,0.001096762,0.0001866068,0.05964754,0.00009674991,0.001205157,0.00007869124],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962051,0.001106622,0.00002615624,0.00008168031,0.0001454851,0.0003626536,0.000004355578,0.000008752051,0.002059193],"genre_scores_gemma":[0.9949513,0.004797169,0.00002081135,0.00004319981,0.00001214201,0.00002164555,0.000001384655,0.000004704447,0.0001476282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3208452,"threshold_uncertainty_score":0.9991024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01587110755572374,"score_gpt":0.247555400221206,"score_spread":0.2316842926654822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}