{"id":"W2154110799","doi":"10.1002/bit.10144","title":"Erythropoietin production from CHO cells grown by continuous culture in a fluidized‐bed bioreactor","year":2001,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Bioreactor; Chinese hamster ovary cell; Microcarrier; Erythropoietin; Cell culture; Fed-batch culture; Chemistry; Chromatography; Ammonia production; Biology; Biochemistry; Food science; Ammonia; Fermentation; Cell; Endocrinology; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003368983,0.0005457321,0.0007672763,0.0002688919,0.0002404365,0.0005603072,0.0006490073,0.0003576415,0.0006609717],"category_scores_gemma":[0.0002142609,0.000221534,0.0006251765,0.0004026589,0.0002194804,0.0003104873,0.0004758215,0.0006939774,0.0008029041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005091926,"about_ca_system_score_gemma":0.0003243987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001734819,"about_ca_topic_score_gemma":0.001373085,"domain_scores_codex":[0.9997646,0.0000410153,0.0000299055,0.00005885972,0.00007432829,0.00003127859],"domain_scores_gemma":[0.9998486,0.00003097023,0.00002032497,0.00003077916,0.00004337814,0.00002580791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008354209,0.00001490878,0.00008672252,0.00003228433,0.000006001347,0.00003625888,0.00002119007,0.00008949971,0.998914,0.00002888773,0.0000383175,0.0006483839],"study_design_scores_gemma":[0.00004743698,0.0002557556,0.001460886,0.00001161538,0.00003086542,0.0001378618,0.00002057086,0.002057443,0.9935538,0.00004354482,0.002367425,0.00001280708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973492,0.0017993,0.01981004,0.0001261535,0.00008948731,0.0001629151,0.001374438,0.0003780535,0.002767636],"genre_scores_gemma":[0.9509022,0.001778629,0.03524379,0.00009007906,0.00006223263,0.0003334329,0.004458274,0.0001821835,0.006949252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001734819,"threshold_uncertainty_score":0.003694415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003701569618643719,"score_gpt":0.202312629083448,"score_spread":0.1986110594648043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}