{"id":"W2154126453","doi":"10.1016/j.ibmb.2014.05.004","title":"High resolution genetic mapping uncovers chitin synthase-1 as the target-site of the structurally diverse mite growth inhibitors clofentezine, hexythiazox and etoxazole in Tetranychus urticae","year":2014,"lang":"en","type":"article","venue":"Insect Biochemistry and Molecular Biology","topic":"Insect-Plant Interactions and Control","field":"Agricultural and Biological Sciences","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Bijzonder Onderzoeksfonds UGent; National Institutes of Health; Vlaamse regering; Universiteit Gent; Fonds Wetenschappelijk Onderzoek; National Institute of General Medical Sciences; Ontario Genomics Institute; University of Utah","keywords":"Tetranychus urticae; Acaricide; Biology; Spider mite; Mode of action; Locus (genetics); Carbamate; Genetics; Panonychus ulmi; Toxicology; Mite; Gene; Biochemistry; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006290984,0.000233875,0.0002194327,0.000252973,0.0001521528,0.0002446843,0.0003191229,0.0003060128,0.0006781468],"category_scores_gemma":[0.00008041063,0.0002191834,0.0002610387,0.000123566,0.0001852717,0.00008967122,0.0001928537,0.0005269013,0.0002840918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022744,"about_ca_system_score_gemma":0.0001829973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001986244,"about_ca_topic_score_gemma":0.004002372,"domain_scores_codex":[0.9999462,0.000006468595,0.000004310632,0.00001455657,0.00001852765,0.000009914431],"domain_scores_gemma":[0.9999127,0.00001748662,0.0000371579,0.000006476403,0.000007477035,0.00001857388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003278695,0.00000649784,0.0001257254,0.0000057226,0.000002015719,0.00002100658,0.00000658475,0.00004349335,0.9993991,0.00004480189,0.000006606583,0.0003056647],"study_design_scores_gemma":[0.00004912023,0.0001346249,0.06207634,0.000009741869,0.00004035748,0.0005608732,0.0001041393,0.00336847,0.9310624,0.0001923377,0.002388992,0.00001240005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969676,0.000288713,0.001675443,0.00006477734,0.000008132492,0.000009982151,0.0002577536,0.00003386561,0.0006938598],"genre_scores_gemma":[0.9963061,0.0001480725,0.001283979,0.00004271316,0.00000221941,0.00000917583,0.0005691085,0.00001999281,0.001618665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001986244,"threshold_uncertainty_score":0.003949404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003761745903198846,"score_gpt":0.180020017257592,"score_spread":0.1762582713543932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}