{"id":"W2154126453","doi":"10.1016/j.ibmb.2014.05.004","title":"High resolution genetic mapping uncovers chitin synthase-1 as the target-site of the structurally diverse mite growth inhibitors clofentezine, hexythiazox and etoxazole in Tetranychus urticae","year":2014,"lang":"en","type":"article","venue":"Insect Biochemistry and Molecular Biology","topic":"Insect-Plant Interactions and Control","field":"Agricultural and Biological Sciences","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Bijzonder Onderzoeksfonds UGent; National Institutes of Health; Vlaamse regering; Universiteit Gent; Fonds Wetenschappelijk Onderzoek; National Institute of General Medical Sciences; Ontario Genomics Institute; University of Utah","keywords":"Tetranychus urticae; Acaricide; Biology; Spider mite; Mode of action; Locus (genetics); Carbamate; Genetics; Panonychus ulmi; Toxicology; Mite; Gene; Biochemistry; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001338114,0.0001460365,0.0001568482,0.00001460432,0.000171801,0.00002360627,0.000145027,0.0001504646,0.00002746921],"category_scores_gemma":[0.0001247231,0.00005597812,0.00007084781,0.0001567295,0.0002175376,0.00002385396,0.00008906423,0.0001851968,0.000001075839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001444638,"about_ca_system_score_gemma":0.00001147201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001432559,"about_ca_topic_score_gemma":0.0003564393,"domain_scores_codex":[0.9990743,0.0001517878,0.0002156301,0.0002675529,0.00007781787,0.0002128838],"domain_scores_gemma":[0.9995935,0.0001280822,0.0001093399,0.00008409663,0.00004021011,0.0000447643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005912128,0.00001738175,0.0121851,0.00001191702,0.00001924692,0.000003400386,0.00005469153,0.00000920664,0.9851592,0.0003411092,0.00002194151,0.002117641],"study_design_scores_gemma":[0.0005295835,0.0002358212,0.2325928,0.00007099355,0.00003166688,0.0001196833,0.0002681236,0.0002002973,0.7627256,0.001798733,0.001190975,0.0002357567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979711,0.0003661354,0.00002058471,0.001097583,0.0001309942,0.0001461399,0.00006557563,0.00001037349,0.0001914913],"genre_scores_gemma":[0.9992055,0.00006736539,0.00006623513,0.0005084308,0.00008995469,0.000009385206,0.00003549514,0.00000123456,0.00001636739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2224337,"threshold_uncertainty_score":0.2282722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003761745903198846,"score_gpt":0.180020017257592,"score_spread":0.1762582713543932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}