{"id":"W2154152591","doi":"10.1021/ol0505959","title":"Allocolchicinoid Synthesis via Direct Arylation","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001986813,0.0001531554,0.0001567886,0.0000600031,0.00009311554,0.00003053335,0.0001552942,0.00008188901,0.01958903],"category_scores_gemma":[0.0002883313,0.000162022,0.00007464244,0.0001928364,0.00003895704,0.0001452178,0.00003930517,0.0001215904,0.0006361898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002684927,"about_ca_system_score_gemma":0.00003234279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002585105,"about_ca_topic_score_gemma":0.00001900705,"domain_scores_codex":[0.9989538,0.00002846168,0.0002477336,0.0002965094,0.0002692866,0.0002042298],"domain_scores_gemma":[0.9991502,0.0002768242,0.0001002874,0.0003679752,0.00003231124,0.00007244124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001043317,0.000030437,0.001143934,0.0000208014,0.0000376198,0.000002443643,0.00008105709,0.0001626475,0.9822283,0.00003227818,0.008441327,0.007808722],"study_design_scores_gemma":[0.0002460989,0.000002130009,0.000970282,0.00001734237,0.00006044505,0.0000234222,0.00001539989,0.001104579,0.9527085,0.0000179533,0.04460468,0.000229126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.860767,0.0001196831,0.07616765,0.03072136,0.0004911493,0.0002206623,0.00002716231,0.0008271734,0.03065817],"genre_scores_gemma":[0.9891494,0.000007672546,0.00404802,0.003881459,0.00100676,0.00003326094,0.00006090946,0.00006295867,0.001749556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1283824,"threshold_uncertainty_score":0.9813072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01037734397866315,"score_gpt":0.232672430666276,"score_spread":0.2222950866876129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}