{"id":"W2154212357","doi":"10.1016/j.bbamcr.2010.01.020","title":"Cytosolic phospholipase A2-α enhances induction of endoplasmic reticulum stress","year":2010,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Endoplasmic reticulum; Unfolded protein response; Tunicamycin; Ionomycin; Phospholipase A2; Dithiothreitol; Biology; Cell biology; Cytosol; Biochemistry; Chemistry; Molecular biology; Intracellular; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006769878,0.001004422,0.0009703439,0.000652299,0.0003617828,0.0008214051,0.000396856,0.0005622486,0.003300469],"category_scores_gemma":[0.00049078,0.000374071,0.0008249391,0.0006088069,0.0005602014,0.0006177279,0.0005965437,0.001740294,0.001132271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006351068,"about_ca_system_score_gemma":0.0006204128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004365975,"about_ca_topic_score_gemma":0.0005224391,"domain_scores_codex":[0.9994214,0.0001361105,0.00007603985,0.00007686263,0.00007529127,0.0002143826],"domain_scores_gemma":[0.9993355,0.0001636603,0.00009103721,0.0001472645,0.00005844234,0.0002041101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003056712,0.0002929903,0.0001462223,0.00007184988,0.00001581791,0.0002100141,0.00003219454,0.00006875319,0.9947593,0.0001706121,0.0001103587,0.001065226],"study_design_scores_gemma":[0.0001324809,0.0007129495,0.001580489,0.000007318088,0.00002266525,0.0001796367,0.00004698987,0.0003762128,0.9958787,0.00005818588,0.000998172,0.000006164035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901415,0.001968188,0.002917611,0.0003679954,0.0003433952,0.0001318514,0.000743918,0.000327217,0.003058362],"genre_scores_gemma":[0.9899626,0.001265019,0.001363052,0.0001345934,0.0001065401,0.0001096541,0.001169037,0.00005705831,0.005832305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003300469,"threshold_uncertainty_score":0.0110411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01476909828163772,"score_gpt":0.3083105064916397,"score_spread":0.293541408210002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}