{"id":"W2154273201","doi":"10.1128/jvi.00539-11","title":"Adenovirus E1A Directly Targets the E2F/DP-1 Complex","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"E2F; Biology; Promoter; Transcription factor; Cell cycle; Cell biology; Transcription (linguistics); Cell Cycle Protein; Adenoviridae; Gene expression; Gene; Molecular biology; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272791,0.0003691034,0.0001620942,0.0002013707,0.0002815443,0.0004445948,0.0002029962,0.0002792517,0.002380925],"category_scores_gemma":[0.0001085586,0.0002011802,0.0001717822,0.0001052295,0.0002802665,0.0002042569,0.0002270522,0.0004728729,0.0009218542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006834379,"about_ca_system_score_gemma":0.0003663014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001394382,"about_ca_topic_score_gemma":0.001343475,"domain_scores_codex":[0.9998783,0.00001987536,0.000005995402,0.00003420757,0.00002808744,0.00003350705],"domain_scores_gemma":[0.9999417,0.00001305474,0.00001222308,0.000007682447,0.000007110891,0.00001806626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002879712,0.00001464213,0.0001416844,0.00001456444,0.000001716604,0.00001967591,0.000005180455,0.00001949525,0.998787,0.0001703718,0.00002921623,0.0007676764],"study_design_scores_gemma":[0.000008259252,0.00008952906,0.003421854,0.000003914838,0.000004614808,0.0001728905,0.00001681845,0.000420631,0.9914626,0.00006557036,0.004330669,0.000002584326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807695,0.003826893,0.009869375,0.0001385696,0.0000571274,0.00005506189,0.0002520305,0.0001365596,0.004894848],"genre_scores_gemma":[0.9880112,0.001217097,0.004142226,0.00004040422,0.00001081032,0.0000245895,0.0004242005,0.00002040027,0.006109041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002380925,"threshold_uncertainty_score":0.007965028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04858200803846373,"score_gpt":0.3090618942319645,"score_spread":0.2604798861935008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}