{"id":"W2154285250","doi":"10.1074/jbc.m809535200","title":"Bidirectional Modulation of Adipogenesis by the Secreted Protein Ccdc80/DRO1/URB","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Adipogenesis; Cell biology; 3T3-L1; Autocrine signalling; Paracrine signalling; Adipocyte; Wnt signaling pathway; Biology; Gene knockdown; Adipose tissue; Cellular differentiation; Signal transduction; Receptor; Chemistry; Cell culture; Endocrinology; Mesenchymal stem cell; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002614883,0.00009599438,0.0002837053,0.00001776634,0.00003540143,0.000004327519,0.00009826817,0.0001623524,0.0002765972],"category_scores_gemma":[0.0002499382,0.0000504342,0.0001598931,0.0001269164,0.00006121385,0.00003080669,0.00001004791,0.0002244957,0.000002008427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002547853,"about_ca_system_score_gemma":0.00005469579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002109302,"about_ca_topic_score_gemma":2.439584e-8,"domain_scores_codex":[0.9991526,0.0000314702,0.0003836255,0.00009316696,0.0002210258,0.0001181315],"domain_scores_gemma":[0.9992449,0.00003818767,0.0003241449,0.0001086935,0.000185929,0.00009814966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002277255,0.0001229037,0.0007710502,0.00001245437,0.00005456465,0.000009468689,0.00001442561,0.000005298321,0.9895471,0.000008248909,0.001233736,0.007993002],"study_design_scores_gemma":[0.0007140774,0.000322434,0.0418844,0.00005977578,0.00007937547,0.0003961257,0.0000278084,0.00004198598,0.9451521,0.0003173792,0.01093524,0.00006930802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945463,0.002994888,0.0001798797,0.00125836,0.00003569081,0.00009477163,0.000006869164,0.00000983797,0.000873432],"genre_scores_gemma":[0.99798,0.0001151027,0.0003637562,0.0001712372,0.000435932,0.000001568599,0.00001263111,0.000003893478,0.0009158615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04439503,"threshold_uncertainty_score":0.3028545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357227414979218,"score_gpt":0.2689484729140066,"score_spread":0.2453761987642144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}