{"id":"W2154295173","doi":"10.1002/glia.10214","title":"Role of the Rap1 GTPase in astrocyte growth regulation","year":2003,"lang":"en","type":"article","venue":"Glia","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; SickKids Foundation; University of Toronto; University Health Network","funders":"National Cancer Institute; National Institutes of Health; National Institute of Neurological Disorders and Stroke; Howard Hughes Medical Institute","keywords":"Astrocyte; Rap1; Biology; Transgene; TSC2; Small GTPase; Genetically modified mouse; Cancer research; Endocrinology; Cell biology; Internal medicine; Signal transduction; Genetics; PI3K/AKT/mTOR pathway; Gene; Central nervous system; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001257461,0.0003495025,0.0001684758,0.0002946951,0.0002243473,0.0004092562,0.0001587655,0.0003117307,0.0004191126],"category_scores_gemma":[0.0001736779,0.0001238201,0.00009509871,0.0001090149,0.0003380082,0.0002028007,0.0002619922,0.0003350657,0.0003017845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002278888,"about_ca_system_score_gemma":0.0001654329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000397264,"about_ca_topic_score_gemma":0.0003927557,"domain_scores_codex":[0.9998944,0.00002945417,0.000005972381,0.00002197909,0.00002500959,0.00002323768],"domain_scores_gemma":[0.9999077,0.00001714239,0.00002644823,0.00001265707,0.00001620881,0.00001983216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002195169,0.00002246409,0.0008472856,0.00007463782,0.000009779032,0.0006116873,0.0000522228,0.0003470863,0.9828264,0.001250297,0.000223688,0.01351497],"study_design_scores_gemma":[0.00004379867,0.0005130465,0.02271601,0.00005160272,0.00006008429,0.006877028,0.0001804214,0.004023313,0.9460524,0.002114153,0.01734769,0.000020425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9667906,0.02326731,0.003368397,0.0005881878,0.0000350348,0.0000125725,0.0001404159,0.0002236176,0.005573843],"genre_scores_gemma":[0.9907415,0.00578951,0.001929945,0.00004022086,0.00001788192,0.00001116839,0.00009789906,0.00001573004,0.001356216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004191126,"threshold_uncertainty_score":0.001653433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01803762917538463,"score_gpt":0.2570764428232261,"score_spread":0.2390388136478414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}