{"id":"W2154313936","doi":"10.1002/jbmr.1782","title":"Pharmacological inhibition of PPARγ increases osteoblastogenesis and bone mass in male C57BL/6 mice","year":2012,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; McGill University","funders":"National Health and Medical Research Council","keywords":"Endocrinology; Internal medicine; Bone mass; Peroxisome proliferator-activated receptor; Medicine; Receptor; Osteoporosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005521465,0.001342419,0.001033712,0.002087402,0.000497418,0.0007053666,0.0008136736,0.001296013,0.003092249],"category_scores_gemma":[0.0001883887,0.001036628,0.0009883497,0.0006870434,0.0009238279,0.0004100771,0.0005005302,0.002569634,0.001220451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007054782,"about_ca_system_score_gemma":0.0006361236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002011502,"about_ca_topic_score_gemma":0.004562119,"domain_scores_codex":[0.9991205,0.00008618608,0.00007846607,0.0002658397,0.0002662695,0.000182629],"domain_scores_gemma":[0.999361,0.00003403034,0.0002506374,0.00004489693,0.00006116134,0.0002483579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001515809,0.0005464239,0.0002825003,0.0000877261,0.00002161522,0.00009310811,0.00003695667,0.000100862,0.9955415,0.0001294291,0.0001116828,0.001532447],"study_design_scores_gemma":[0.001101767,0.008434061,0.01932228,0.0001113483,0.0002505365,0.0007773435,0.0002881135,0.001382647,0.9584373,0.0003549142,0.009477626,0.0000621393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807512,0.006497486,0.004693453,0.0008489453,0.0002201034,0.0002127147,0.003597547,0.0005059918,0.002672583],"genre_scores_gemma":[0.9360008,0.01168333,0.01293223,0.001293886,0.0001663006,0.0009140788,0.004692369,0.0003431263,0.03197407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003092249,"threshold_uncertainty_score":0.01034462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03652402777592113,"score_gpt":0.3409615914302977,"score_spread":0.3044375636543766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}