{"id":"W2154387982","doi":"10.1038/emboj.2008.22","title":"ShcA signalling is essential for tumour progression in mouse models of human breast cancer","year":2008,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":159,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; McGill University; Lunenfeld-Tanenbaum Research Institute; McGill University Health Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research; Terry Fox Foundation; Canadian Breast Cancer Research Alliance","keywords":"Biology; Breast cancer; Human breast; Cancer; Signalling; Cancer research; Computational biology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003971701,0.0005806139,0.0003487321,0.001617569,0.0005146438,0.001020368,0.0005348157,0.0008063875,0.006024238],"category_scores_gemma":[0.0003124457,0.0007439347,0.0005792627,0.0004645652,0.0006969761,0.0006750472,0.0004240579,0.002299723,0.001613881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008986809,"about_ca_system_score_gemma":0.0005470036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001991905,"about_ca_topic_score_gemma":0.003319383,"domain_scores_codex":[0.9993887,0.0000627375,0.00004564063,0.0001346554,0.0002090875,0.0001591991],"domain_scores_gemma":[0.9994491,0.00007697099,0.0001662554,0.00008570666,0.00005630265,0.0001657376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000377136,0.00005002727,0.0002783159,0.00006967338,0.00001526495,0.00008689618,0.00002189702,0.0001262573,0.9961055,0.0006313554,0.0004054047,0.001832183],"study_design_scores_gemma":[0.00009641545,0.0002446115,0.005584723,0.00002723169,0.00006079594,0.0005807713,0.00006733793,0.001804518,0.9795725,0.0004423425,0.01150538,0.00001332155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9656655,0.008853115,0.009113495,0.001498038,0.000371182,0.00009053497,0.004672116,0.0008041193,0.008931907],"genre_scores_gemma":[0.9778494,0.002653264,0.003021144,0.0001808799,0.0000585923,0.0001331756,0.001908458,0.0001872741,0.01400782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006024238,"threshold_uncertainty_score":0.02015311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06703470165791008,"score_gpt":0.3803124353803284,"score_spread":0.3132777337224184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}