{"id":"W2154396014","doi":"10.1128/mcb.01162-10","title":"La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institutes of Health; Wellcome Trust","keywords":"Biology; Poly(A)-binding protein; RNA-binding protein; Messenger RNA; Polysome; RNA; Ribosome; Binding protein; RNA recognition motif; Molecular biology; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008673293,0.0003235228,0.0002726307,0.00007896894,0.0002733104,0.00008651234,0.0002781354,0.0004014189,0.00002938342],"category_scores_gemma":[0.0001056908,0.0002133651,0.00007765642,0.0001604731,0.0006128057,0.000007824177,0.0003055327,0.000645181,0.000002901965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001420787,"about_ca_system_score_gemma":0.0001265686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003186446,"about_ca_topic_score_gemma":0.0003381606,"domain_scores_codex":[0.9977927,0.0004887363,0.0002641452,0.0007074156,0.0001480552,0.000598916],"domain_scores_gemma":[0.9989748,0.00002159142,0.000120998,0.0005627067,0.00007589108,0.0002439942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001802778,0.00007199642,0.0004982018,0.00003489863,0.0001216932,0.0001150311,0.0001697874,1.817685e-7,0.9922138,0.0006267077,0.000004111374,0.005963314],"study_design_scores_gemma":[0.001017659,0.0008989593,0.0001818278,0.00003023937,0.00002259026,0.0002361972,0.0001615874,0.0001038598,0.9947745,0.0004347538,0.001826599,0.0003111968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923246,0.0008921761,0.004168908,0.001184331,0.00004074944,0.001052757,0.00002491643,0.00002119338,0.0002903937],"genre_scores_gemma":[0.9981675,0.00001069864,0.0009976431,0.00007979396,0.00004359663,0.0001342223,0.0001202877,0.00004219855,0.0004040923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005842891,"threshold_uncertainty_score":0.8700776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004148286165741317,"score_gpt":0.213691670795386,"score_spread":0.2095433846296447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}