{"id":"W2154396014","doi":"10.1128/mcb.01162-10","title":"La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institutes of Health; Wellcome Trust","keywords":"Biology; Poly(A)-binding protein; RNA-binding protein; Messenger RNA; Polysome; RNA; Ribosome; Binding protein; RNA recognition motif; Molecular biology; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007548992,0.000348758,0.0001863327,0.000181144,0.000238554,0.0002400489,0.0001765705,0.0002429179,0.001895457],"category_scores_gemma":[0.0001173047,0.0001206365,0.0003903398,0.0001279544,0.0002134597,0.0001450634,0.0002605275,0.0003585045,0.001018416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003820968,"about_ca_system_score_gemma":0.0001277737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003083822,"about_ca_topic_score_gemma":0.0004852092,"domain_scores_codex":[0.9999412,0.00001188007,0.000002894477,0.00001859762,0.00001341864,0.00001194328],"domain_scores_gemma":[0.9999336,0.00001074303,0.00002448443,0.000006336236,0.000006480362,0.00001842789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007721232,0.00001772716,0.0006216026,0.00003010586,0.000009964804,0.00006606909,0.000005327462,0.00006657318,0.9971847,0.00008732805,0.0001177501,0.001715612],"study_design_scores_gemma":[0.00002437933,0.0003613346,0.01834818,0.000008370435,0.00003338463,0.0006908558,0.00003032657,0.002652942,0.9666596,0.000180351,0.0109992,0.0000110153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890681,0.002680215,0.00533485,0.0001370005,0.00003061921,0.00002254404,0.0002240087,0.0002443043,0.002258329],"genre_scores_gemma":[0.9860072,0.0008014418,0.005616561,0.0001036392,0.00002495516,0.00003257608,0.00139145,0.000040887,0.005981339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001895457,"threshold_uncertainty_score":0.006340921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004148286165741317,"score_gpt":0.213691670795386,"score_spread":0.2095433846296447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}