{"id":"W2154450305","doi":"10.1002/jcp.22853","title":"Cdc42 negatively regulates intrinsic migration of highly aggressive breast cancer cells","year":2011,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"CDC42; RHOA; Cell migration; RAC1; Cell biology; Cancer cell; Kinase; Signal transduction; Biology; Gene silencing; Protein kinase C; Cancer research; Chemistry; Cell; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001536086,0.0001388233,0.0002801758,0.00009446131,0.00003760122,0.000004301929,0.0001689903,0.0001482782,0.0001092111],"category_scores_gemma":[0.00002424383,0.0001133051,0.0001750707,0.00009452082,0.0001428073,0.00001158003,0.00004896265,0.0001100837,0.000002683949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001469217,"about_ca_system_score_gemma":0.0001178434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004615264,"about_ca_topic_score_gemma":0.000008573937,"domain_scores_codex":[0.9989889,0.0001376209,0.0004399436,0.0001565589,0.0001212396,0.0001557811],"domain_scores_gemma":[0.9981931,0.00001101656,0.001126315,0.0001655675,0.000431267,0.00007267806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004721214,0.00009027881,0.0001616168,0.00002832005,0.0001139841,0.00001013339,0.0001473684,0.0001388523,0.9965658,0.0001148295,0.0003189029,0.001837789],"study_design_scores_gemma":[0.000551802,0.0003320818,0.01197773,0.00007069568,0.00004367558,0.000045931,0.000045148,0.00004393534,0.9853854,0.0006913483,0.0006961297,0.0001160879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966151,0.001899408,0.001036353,0.00008119739,0.0001916253,0.00009021639,0.00001929789,0.00000286566,0.00006400584],"genre_scores_gemma":[0.9981598,0.0004218705,0.0008453446,0.00007471085,0.0003996402,0.000003352352,0.0000148899,0.00001490969,0.0000655434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01181612,"threshold_uncertainty_score":0.4620446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138141762150701,"score_gpt":0.2216484948107783,"score_spread":0.2102670771892713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}