{"id":"W2154473763","doi":"10.4155/bio.14.279","title":"2014 White Paper on Recent Issues in Bioanalysis: A Full Immersion in Bioanalysis (Part 2 – Hybrid LBA/LCMS, ELN & Regulatory Agencies’ Input)","year":2014,"lang":"en","type":"article","venue":"Bioanalysis","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"inVentiv Health Clinical; Health Canada; Armand Frappier Museum","funders":"","keywords":"Bioanalysis; Biopharmaceutical; Computer science; White paper; Nanotechnology; Engineering ethics; Political science; Engineering; Materials science; Biotechnology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01908699,0.00137686,0.001017537,0.002090874,0.003200586,0.01089665,0.002886906,0.01141972,0.031542],"category_scores_gemma":[0.018945,0.001109307,0.001532728,0.001643947,0.003297437,0.006574572,0.003839681,0.0104927,0.02659353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004485524,"about_ca_system_score_gemma":0.0137312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002779621,"about_ca_topic_score_gemma":0.004179683,"domain_scores_codex":[0.9865865,0.001523068,0.0007068204,0.00138663,0.008771968,0.001025128],"domain_scores_gemma":[0.9773752,0.00361091,0.001438914,0.001127751,0.0125801,0.003867114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002797309,0.0000429864,0.00005055138,0.0001619665,0.000007317866,0.00006968775,0.0001002861,0.00006114606,0.001404199,0.004086656,0.965959,0.02802819],"study_design_scores_gemma":[0.000004029772,0.00001784062,0.00008428435,0.0000896636,0.000003696968,0.00003497048,0.00004171069,0.00002819647,0.0009309035,0.001223404,0.9975331,0.000008121583],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"commentary","genre_scores_codex":[0.001587826,0.03583881,0.01155595,0.3479047,0.5165179,0.0004037913,0.001076702,0.00079597,0.08431841],"genre_scores_gemma":[0.00873246,0.03796919,0.01544284,0.1926727,0.1455216,0.0004262185,0.002204377,0.001594538,0.5954362],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.031542,"threshold_uncertainty_score":0.1055185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0202534522797612,"score_gpt":0.2752489872493901,"score_spread":0.2549955349696288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}