{"id":"W2154476236","doi":"10.1099/vir.0.032193-0","title":"NS1-mediated delay of type I interferon induction contributes to influenza A virulence in ferrets","year":2011,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Armand-Frappier Foundation","keywords":"Virulence; Biology; Virology; Recombinant DNA; Interferon; Virus; Microbiology; Strain (injury); In vitro; Interferon type I; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001877516,0.0004405901,0.0003862438,0.0003194523,0.0002123947,0.0003675298,0.0001889646,0.0004550629,0.0007186349],"category_scores_gemma":[0.0002649654,0.0001863407,0.000342528,0.00006094396,0.000541796,0.0003323238,0.0001853828,0.0007841591,0.0002799546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000629867,"about_ca_system_score_gemma":0.0001809765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000576684,"about_ca_topic_score_gemma":0.000643116,"domain_scores_codex":[0.9998429,0.00002765596,0.00001209131,0.00005021611,0.0000252244,0.00004185946],"domain_scores_gemma":[0.999772,0.00005262361,0.0000854243,0.00002576024,0.00001797127,0.0000462033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002355521,0.0000294021,0.0007407244,0.00001935077,0.000003705796,0.00008023983,0.00003059773,0.00003446402,0.9982621,0.00003370736,0.00001896247,0.0005112833],"study_design_scores_gemma":[0.0000380667,0.001859405,0.03922861,0.0000154745,0.00004475743,0.00121314,0.0002130175,0.001252472,0.9545413,0.0002230131,0.001352748,0.0000180137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988201,0.0003917701,0.0003290319,0.00004354317,0.00001230973,0.00000988005,0.00007373227,0.00002270104,0.0002968499],"genre_scores_gemma":[0.998287,0.0002112906,0.0003598334,0.00003370775,0.00001147487,0.00002387957,0.0001526648,0.000013482,0.000906626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007186349,"threshold_uncertainty_score":0.004570067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1327296850329667,"score_gpt":0.3846983836124239,"score_spread":0.2519686985794573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}