{"id":"W2154488194","doi":"10.1002/hep.22658","title":"Early hepatitis B virus DNA reduction in hepatitis B e antigen–positive patients with chronic hepatitis B","year":2008,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":181,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Adefovir; Entecavir; Hepatitis B virus; Medicine; Hepatitis B; Virology; Viral load; Gastroenterology; Internal medicine; Virus; Lamivudine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008311903,0.0002206179,0.0006560604,0.0000809556,0.0001501761,0.0002380632,0.0001139229,0.0003194091,0.001221317],"category_scores_gemma":[0.001484869,0.0001063082,0.0002619629,0.00009415729,0.0002000018,0.0002580787,0.000119611,0.0004380093,0.0001690256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001379274,"about_ca_system_score_gemma":0.0001985015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002253777,"about_ca_topic_score_gemma":0.0004673739,"domain_scores_codex":[0.9996715,0.0001736482,0.00003550179,0.0000381565,0.00004965221,0.00003152816],"domain_scores_gemma":[0.9991486,0.0004070789,0.0001961678,0.00002315732,0.00006175414,0.000163239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2804785,0.009424158,0.3760868,0.001450245,0.0008552823,0.0003206091,0.0003680854,0.001118194,0.03090444,0.0001058773,0.0009138829,0.2979739],"study_design_scores_gemma":[0.03165837,0.2357175,0.7200961,0.0001654193,0.0006016541,0.001173335,0.000206022,0.001216839,0.00526524,0.0001543006,0.003716337,0.00002881509],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997973,0.001558134,0.00007518459,0.00006513197,0.00001600888,0.00003315126,0.00003251725,0.000003595751,0.000243313],"genre_scores_gemma":[0.9990444,0.0003439242,0.0002229606,0.0001068758,0.00003358765,0.00002922671,0.00005903818,8.130704e-7,0.000159178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001221317,"threshold_uncertainty_score":0.004395783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01239382790669697,"score_gpt":0.2394863931354969,"score_spread":0.2270925652287999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}