{"id":"W2154488194","doi":"10.1002/hep.22658","title":"Early hepatitis B virus DNA reduction in hepatitis B e antigen–positive patients with chronic hepatitis B","year":2008,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":181,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Adefovir; Entecavir; Hepatitis B virus; Medicine; Hepatitis B; Virology; Viral load; Gastroenterology; Internal medicine; Virus; Lamivudine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001498316,0.0006052507,0.001291028,0.0006077585,0.0004142814,0.00002038115,0.0001968065,0.0003974211,0.0004285763],"category_scores_gemma":[0.0001789752,0.0005799475,0.0001734132,0.0008904182,0.0008196227,0.0004081258,0.0001413081,0.0006356264,0.0004685922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001147791,"about_ca_system_score_gemma":0.0005636155,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.2067887,"about_ca_topic_score_gemma":0.2055318,"domain_scores_codex":[0.9959639,0.0003012132,0.0008992523,0.001021144,0.0006860972,0.001128435],"domain_scores_gemma":[0.9980462,0.0001249397,0.0003170487,0.0006726891,0.0005375603,0.0003015277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003686635,0.000563065,0.990419,0.00006809529,0.000223669,0.001595986,0.001529235,0.00000258303,0.0004836589,0.0001582713,0.001852578,0.002735239],"study_design_scores_gemma":[0.003587303,0.002694027,0.9861908,0.0002598659,0.00009104815,0.0006988142,0.00000594747,0.0001926028,0.003418674,0.00006748449,0.002212424,0.0005809955],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994154,0.0008454829,0.0001490071,0.0005146697,0.0006875194,0.001429305,0.0001863458,0.0002343293,0.001799329],"genre_scores_gemma":[0.9834536,0.01391297,0.0008223528,0.0004670909,0.0002759514,0.000286566,0.0002873399,0.0001214067,0.000372698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01306748,"threshold_uncertainty_score":0.9996652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01239382790669697,"score_gpt":0.2394863931354969,"score_spread":0.2270925652287999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}