{"id":"W2154567430","doi":"10.1210/jc.2010-2648","title":"Circulating Estrogens in Endometrial Cancer Cases and Their Relationship with Tissular Expression of Key Estrogen Biosynthesis and Metabolic Pathways","year":2010,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Endometrial cancer; Estrogen; Biosynthesis; Internal medicine; Endocrinology; Chemistry; Metabolic pathway; Cancer research; Metabolism; Cancer; Biology; Cell biology; Biochemistry; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001241665,0.0001967002,0.0006786563,0.0001536439,0.00008907214,0.00001009995,0.0002108731,0.0002660317,0.0000063959],"category_scores_gemma":[0.00251829,0.0001079504,0.0001527821,0.0001629993,0.0005140093,0.00001554036,0.0001100101,0.0007883967,3.166959e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001963013,"about_ca_system_score_gemma":0.0001365389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004751987,"about_ca_topic_score_gemma":0.00002224025,"domain_scores_codex":[0.9978623,0.0006601349,0.0008653624,0.0002082292,0.0001365447,0.000267367],"domain_scores_gemma":[0.9972955,0.001453853,0.0007223437,0.0002695642,0.0001255595,0.0001332094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001057944,0.000110378,0.1399869,0.00001093703,0.0002812466,0.00005910822,0.0001817332,0.0000464603,0.8435313,0.0008101794,0.000008464814,0.01391543],"study_design_scores_gemma":[0.004336258,0.0006196116,0.1655212,0.00006356712,0.0005182789,0.002834249,0.0002596501,0.00002873828,0.8228763,0.0003900033,0.002343818,0.0002083753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686514,0.03063765,0.00004924358,0.0002156338,0.0002496041,0.0001596266,0.00001228666,0.00000380058,0.00002081848],"genre_scores_gemma":[0.9905914,0.007768869,0.001103578,0.00004556236,0.0004577226,0.000005271585,0.000002095429,0.00002025441,0.000005265642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02553427,"threshold_uncertainty_score":0.4402089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03248480614777006,"score_gpt":0.3190012904067677,"score_spread":0.2865164842589977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}