{"id":"W2154624665","doi":"10.1016/j.bbamem.2015.01.011","title":"Fusion-competent state induced by a C-terminal HIV-1 fusion peptide in cholesterol-rich membranes","year":2015,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Eusko Jaurlaritza; Foundation for the National Institutes of Health","keywords":"Vesicle; Lipid bilayer fusion; Gp41; Membrane; Transmembrane protein; Lipid bilayer; Fusion; Liposome; Transmembrane domain; Biophysics; Cell biology; Peptide; Biology; Vesicle fusion; Glycoprotein; Cell membrane; Chemistry; Biochemistry; Antibody; Synaptic vesicle; Epitope; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002350356,0.0002205227,0.000228352,0.0002094271,0.0004003232,0.0004391173,0.0002839435,0.0003026936,0.001346236],"category_scores_gemma":[0.0003429856,0.0001433423,0.0003125696,0.0001859605,0.0003263894,0.0004599923,0.0002598545,0.0007936966,0.0003671075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005248754,"about_ca_system_score_gemma":0.0002588639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001305495,"about_ca_topic_score_gemma":0.000725023,"domain_scores_codex":[0.9998376,0.0000332201,0.00001330367,0.00002142524,0.00003188202,0.00006251557],"domain_scores_gemma":[0.9998183,0.00006946221,0.00002755816,0.0000281259,0.00002264092,0.00003395027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003117643,0.0000461257,0.0001456262,0.00002932635,0.0000109721,0.0001454598,0.00009546473,0.00006294321,0.9983146,0.0004688193,0.00003650044,0.0003322809],"study_design_scores_gemma":[0.0000302898,0.0001681665,0.00188317,0.000008004618,0.00001890169,0.0001976558,0.00006437013,0.0009041864,0.9958951,0.0001587213,0.0006609736,0.00001044039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998351,0.0002355717,0.0005048857,0.00004184095,0.00001461127,0.00001286529,0.0001257085,0.0000184174,0.0006950287],"genre_scores_gemma":[0.9985933,0.0001239655,0.0002637829,0.00001776171,0.000004582208,0.000008526114,0.0002440898,0.000009224697,0.0007348716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001346236,"threshold_uncertainty_score":0.004503608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02421332437522433,"score_gpt":0.2702887655888127,"score_spread":0.2460754412135883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}