{"id":"W2154626801","doi":"10.2337/dc11-0560","title":"Development of Autoantibodies in the TrialNet Natural History Study","year":2011,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Center for Complementary and Alternative Medicine; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Juvenile Diabetes Research Foundation International; National Institutes of Health; American Diabetes Association","keywords":"Medicine; Natural history; Autoantibody; Diabetes mellitus; Natural (archaeology); Immunology; Internal medicine; Endocrinology; Antibody; Archaeology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002462201,0.000218479,0.0003017161,0.0002746138,0.0003502255,0.0006700564,0.0002843769,0.0004012094,0.001374043],"category_scores_gemma":[0.004696508,0.0002114444,0.000310559,0.0005396025,0.000231621,0.0004763597,0.0004186177,0.0004759874,0.0001757288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003367136,"about_ca_system_score_gemma":0.0004904666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003540387,"about_ca_topic_score_gemma":0.004750136,"domain_scores_codex":[0.998612,0.0008390614,0.00008493492,0.0001937228,0.0001693613,0.0001008311],"domain_scores_gemma":[0.996249,0.0007238201,0.002161892,0.0002523717,0.0001911983,0.0004216177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001330879,0.00005575841,0.9968494,0.00002091738,0.00008485594,0.0001162404,0.00004814287,0.00005266906,0.000115765,0.00004859163,0.0003999448,0.0008767552],"study_design_scores_gemma":[0.0002706161,0.0004515254,0.9967116,0.00004194357,0.00009789473,0.0005819721,0.00009840148,0.0005864901,0.00008241778,0.0001037302,0.0009656889,0.000007675455],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997759,0.0006220852,0.00008102722,0.0001256241,0.00002392639,0.00002157282,0.0005921764,0.000002844603,0.0007717384],"genre_scores_gemma":[0.9986772,0.0001606636,0.00010547,0.00006594515,0.00002179187,0.00002123779,0.0005990654,0.000003225894,0.0003453968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003540387,"threshold_uncertainty_score":0.01302153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01605242854676999,"score_gpt":0.2257461872254568,"score_spread":0.2096937586786868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}