{"id":"W2154634067","doi":"10.1200/jco.2004.05.122","title":"Activity and Safety of the Antiestrogen EM-800, the Orally Active Precursor of Acolbifene, in Tamoxifen-Resistant Breast Cancer","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec; Hôpital du Saint-Sacrement; Centre Hospitalier Universitaire de Sherbrooke","funders":"","keywords":"Tamoxifen; Antiestrogen; Medicine; Breast cancer; Internal medicine; Estrogen receptor; Mammary gland; Estrogen; Cancer; Endometrium; Endometrial cancer; Oncology; Endocrinology; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004121303,0.0002199293,0.0004052064,0.0001152753,0.00008959146,0.0001644241,0.0001894737,0.0002543314,0.0006313625],"category_scores_gemma":[0.000539303,0.0001035677,0.0001613554,0.000104214,0.0002414657,0.0001640853,0.00008349596,0.0003580965,0.0001727052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001665325,"about_ca_system_score_gemma":0.0001704021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002496075,"about_ca_topic_score_gemma":0.0005704513,"domain_scores_codex":[0.9998437,0.00008176205,0.000013744,0.00001492572,0.00003021762,0.00001555614],"domain_scores_gemma":[0.9998063,0.0000639155,0.00006850824,0.00001053523,0.00001792629,0.00003287541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1046781,0.009671433,0.07797298,0.0009999964,0.0005736278,0.001211455,0.0002901302,0.002641882,0.379953,0.0001630252,0.001247898,0.4205965],"study_design_scores_gemma":[0.04752703,0.5311638,0.2483996,0.0001830907,0.001216994,0.008333702,0.0003529892,0.005788548,0.1435574,0.0001433227,0.01328501,0.00004871797],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968308,0.002638661,0.00009927019,0.00003202927,0.000005376438,0.00002745389,0.00003389372,0.000004497969,0.0003280623],"genre_scores_gemma":[0.9976401,0.001474167,0.0002971678,0.00006585394,0.00002387479,0.0000324173,0.0002121332,0.000002047746,0.0002522242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006313625,"threshold_uncertainty_score":0.002179623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0210743214959124,"score_gpt":0.3658850163303833,"score_spread":0.3448106948344709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}