{"id":"W2154635407","doi":"10.1128/aac.00786-09","title":"In Vitro Activity of Colistin (Polymyxin E) against 3,480 Isolates of Gram-Negative Bacilli Obtained from Patients in Canadian Hospitals in the CANWARD Study, 2007-2008","year":2009,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Health Sciences Centre","funders":"","keywords":"Colistin; Polymyxin; Bacilli; Microbiology; Gram; Polymyxin B; Gram-negative bacteria; In vitro; Medicine; Gram-negative bacterial infections; Biology; Antibiotics; Bacteria; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003245042,0.000392907,0.0006519249,0.0004106146,0.0005540536,0.0004909498,0.0002525469,0.0003045065,0.0007057495],"category_scores_gemma":[0.001074161,0.0001838677,0.0002033188,0.0009552148,0.0004962343,0.000126493,0.0001966212,0.0003259121,0.0001519849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002755994,"about_ca_system_score_gemma":0.002665254,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.3833643,"about_ca_topic_score_gemma":0.5403328,"domain_scores_codex":[0.9995669,0.0000393571,0.00002874165,0.00006196373,0.0002152967,0.00008773072],"domain_scores_gemma":[0.9994809,0.0001043566,0.00008890668,0.00001934958,0.0001816135,0.0001249836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01515041,0.001209553,0.6514955,0.001496079,0.0003868574,0.002489232,0.00264352,0.001135949,0.2557537,0.0002011687,0.004176389,0.06386165],"study_design_scores_gemma":[0.0003130466,0.006177819,0.9294973,0.00007917632,0.0002084908,0.002388623,0.001099676,0.0007002072,0.05236938,0.0000329238,0.007093727,0.00003974362],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953315,0.002693844,0.00006768971,0.0000772771,0.0000080032,0.00003782538,0.0009094547,0.000008649646,0.0008658633],"genre_scores_gemma":[0.9941998,0.00183067,0.0006956645,0.0001378172,0.00002123117,0.0000162955,0.002218886,0.000004994552,0.000874647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6166357,"threshold_uncertainty_score":0.7622658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005502450244442302,"score_gpt":0.2336646815978924,"score_spread":0.2281622313534501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}