{"id":"W2154655470","doi":"10.1099/mic.0.021931-0","title":"Probiotics prevent enterohaemorrhagic Escherichia coli O157 : H7-mediated inhibition of interferon-γ-induced tyrosine phosphorylation of STAT-1","year":2009,"lang":"en","type":"article","venue":"Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Lactobacillus rhamnosus; STAT protein; Biology; stat; Phosphorylation; Lactobacillus helveticus; Interferon; Microbiology; Tyrosine phosphorylation; JAK-STAT signaling pathway; Signal transduction; Interferon gamma; Molecular biology; Probiotic; Cytokine; Tyrosine kinase; Lactobacillus; Cell biology; Bacteria; Virology; Immunology; STAT3","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001789863,0.0001994684,0.0003355832,0.00007042931,0.00003813155,0.000004199334,0.0001783011,0.0002483749,0.00002212548],"category_scores_gemma":[0.000170793,0.000187243,0.0001209979,0.0002096739,0.0001615928,0.000005255457,0.0001969142,0.0001509836,0.000004012328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004793119,"about_ca_system_score_gemma":0.0001203794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001564734,"about_ca_topic_score_gemma":0.00004642676,"domain_scores_codex":[0.9986598,0.00016823,0.0004571902,0.000340822,0.0000695482,0.0003043572],"domain_scores_gemma":[0.9990626,0.00001612163,0.0002891675,0.0003160868,0.0002652201,0.00005080477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003268977,0.0003870444,0.001433376,0.00006579821,0.00006635366,9.595464e-7,0.00007593282,0.00001648717,0.9964281,0.000021547,0.0007168974,0.0004606418],"study_design_scores_gemma":[0.000835494,0.002202128,0.008228795,0.0000675407,0.000020992,0.00000496332,0.00002812712,0.00003315225,0.9876873,0.00002557672,0.0007112333,0.0001547125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981083,0.0005206537,0.0002310907,0.0001714093,0.0001559429,0.0004914625,0.0001107216,0.00001239462,0.0001980403],"genre_scores_gemma":[0.9983367,0.0001295645,0.0007863762,0.0001460968,0.00004416457,0.00001036835,0.0003532508,0.00001550038,0.0001779816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008740778,"threshold_uncertainty_score":0.7635548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190780300451044,"score_gpt":0.2565434062111747,"score_spread":0.2446356032066643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}