{"id":"W2154655470","doi":"10.1099/mic.0.021931-0","title":"Probiotics prevent enterohaemorrhagic Escherichia coli O157 : H7-mediated inhibition of interferon-γ-induced tyrosine phosphorylation of STAT-1","year":2009,"lang":"en","type":"article","venue":"Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Lactobacillus rhamnosus; STAT protein; Biology; stat; Phosphorylation; Lactobacillus helveticus; Interferon; Microbiology; Tyrosine phosphorylation; JAK-STAT signaling pathway; Signal transduction; Interferon gamma; Molecular biology; Probiotic; Cytokine; Tyrosine kinase; Lactobacillus; Cell biology; Bacteria; Virology; Immunology; STAT3","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442394,0.0004074189,0.0005063395,0.0001295669,0.000111914,0.0003199327,0.0001840543,0.0003325599,0.001273968],"category_scores_gemma":[0.0001473598,0.0001529005,0.0002089626,0.00009583154,0.0001940147,0.0001290525,0.0003709532,0.0005153801,0.0003271576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001575582,"about_ca_system_score_gemma":0.0002735315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006004737,"about_ca_topic_score_gemma":0.001219578,"domain_scores_codex":[0.9998472,0.00002683374,0.00002211101,0.00001976668,0.00003333352,0.00005070284],"domain_scores_gemma":[0.9999025,0.00001443777,0.00002748277,0.000007744023,0.00001329885,0.00003446325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008057311,0.0001308672,0.0001860882,0.00005614301,0.000007996819,0.00004209021,0.00002083165,0.00002356357,0.9974444,0.00001563283,0.0000318927,0.001234889],"study_design_scores_gemma":[0.0001046715,0.003588283,0.01621782,0.00003697991,0.00003639139,0.0001682105,0.0001268148,0.0004438032,0.9775282,0.00002847852,0.001713656,0.000006876138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976623,0.001162872,0.0003021639,0.00006632149,0.00002594565,0.00002323015,0.0001389088,0.00002555317,0.0005926469],"genre_scores_gemma":[0.9949994,0.0008888186,0.0008453909,0.00009063926,0.00001314042,0.00003657592,0.0005497739,0.00001321331,0.002563056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001273968,"threshold_uncertainty_score":0.004261792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190780300451044,"score_gpt":0.2565434062111747,"score_spread":0.2446356032066643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}