{"id":"W2154694193","doi":"10.1016/s0140-6736(11)60886-6","title":"Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial","year":2011,"lang":"en","type":"article","venue":"The Lancet","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":601,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; Sanofi; Novo Nordisk; MacroGenics; University of Florida; U.S. National Library of Medicine; University of Washington","keywords":"Abatacept; Medicine; Placebo; Double blind; Type 2 diabetes; Internal medicine; Diabetes mellitus; Endocrinology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003108268,0.0001404302,0.0003091914,0.00003125877,0.00005649196,0.00002356379,0.0001440431,0.00009022853,0.0000480063],"category_scores_gemma":[0.00005261701,0.00008312011,0.00003662236,0.000129463,0.00004278977,0.000009216068,0.00001375913,0.00008599315,0.000006857129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001357978,"about_ca_system_score_gemma":0.00004190033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001133332,"about_ca_topic_score_gemma":0.00005095683,"domain_scores_codex":[0.9991121,0.0001089674,0.0001815288,0.0002026269,0.0001414152,0.0002533262],"domain_scores_gemma":[0.9994175,0.00002581262,0.0001537571,0.0002822165,0.00008875295,0.00003191754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8880783,0.0001817244,0.1097826,0.000004089314,0.000138133,1.571813e-7,0.000101405,0.0005181989,0.0001376112,0.00000477196,0.0005445144,0.0005084476],"study_design_scores_gemma":[0.9692223,0.001061949,0.02809954,0.00001706433,0.00005706076,4.816334e-8,0.00002542771,0.0002740173,0.0006021915,0.00003094835,0.0004448655,0.0001645601],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957392,0.00005961703,0.00002805198,0.00007287762,0.00007682542,0.002077783,0.00001492717,0.00001376418,0.001916905],"genre_scores_gemma":[0.9988157,0.00003472871,0.00007851892,0.0001556824,0.000122606,0.0001637343,0.0005242318,0.00001969389,0.00008509578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08168306,"threshold_uncertainty_score":0.338954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02108456382828209,"score_gpt":0.2501951088072258,"score_spread":0.2291105449789438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}