{"id":"W2154739626","doi":"10.1093/hmg/ddu362","title":"The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease","year":2014,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; New Brunswick Innovation Foundation","keywords":"Kidney disease; Biology; Type 2 diabetes; Diabetic nephropathy; Single-nucleotide polymorphism; Genome-wide association study; Internal medicine; Population; Genetics; Endocrinology; Diabetes mellitus; Gene; Medicine; Genotype","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001667297,0.000223339,0.0002475436,0.00006887238,0.0003100224,0.00007703844,0.0001338508,0.00008568326,0.00008135096],"category_scores_gemma":[0.0005809863,0.000171884,0.0002401574,0.0001347981,0.0001170106,0.00002221166,0.00002941122,0.0001113838,0.00001211457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005464031,"about_ca_system_score_gemma":0.0001812461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001081493,"about_ca_topic_score_gemma":0.0000096126,"domain_scores_codex":[0.9985835,0.00009251199,0.0002704004,0.0003151923,0.0003406268,0.0003977847],"domain_scores_gemma":[0.9985878,0.00007162336,0.0001140248,0.0004590201,0.0002982778,0.0004692105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005281315,0.0001907597,0.004526614,0.00017343,0.0002993971,0.00001413538,0.0003137266,0.00003148636,0.9894529,0.0006366944,0.002525084,0.001307648],"study_design_scores_gemma":[0.006544903,0.001821558,0.6473848,0.0002928858,0.001547805,0.000001970561,0.00009279566,0.00574041,0.146611,0.001971422,0.1871724,0.00081809],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915771,0.003722254,0.001774743,0.0008841482,0.0001785635,0.0007052125,0.001044699,0.00004539221,0.00006782886],"genre_scores_gemma":[0.9943988,0.0003694149,0.0002288646,0.002918636,0.0001130251,0.00005866383,0.000669171,0.000059268,0.001184123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8428419,"threshold_uncertainty_score":0.7009225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02398048726316444,"score_gpt":0.2906880778932937,"score_spread":0.2667075906301293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}