{"id":"W2154902409","doi":"10.1152/ajpgi.00438.2005","title":"IL-10 protects mouse intestinal epithelial cells from Fas-induced apoptosis via modulating Fas expression and altering caspase-8 and FLIP expression","year":2006,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Apoptosis; Fas ligand; Cytokine; Fas receptor; Molecular biology; Caspase 8; Tumor necrosis factor alpha; Annexin; Biology; Chemistry; Programmed cell death; Caspase 3; Cancer research; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001698656,0.0004360786,0.0002673652,0.0002406876,0.00009123681,0.000288588,0.0002206863,0.0003024522,0.001089978],"category_scores_gemma":[0.0001071202,0.0001770761,0.0002421289,0.0001076855,0.0002097261,0.0002551606,0.0001561502,0.0008824104,0.0003034886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002468113,"about_ca_system_score_gemma":0.0002563142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000429391,"about_ca_topic_score_gemma":0.0007638355,"domain_scores_codex":[0.9998437,0.00002712091,0.00001867432,0.00001994005,0.00003033629,0.00006010786],"domain_scores_gemma":[0.9998554,0.00002244669,0.00004239964,0.00002083149,0.00001972758,0.00003912958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002689038,0.00008642303,0.0001797079,0.00004980125,0.000005424509,0.00005268408,0.00001413973,0.00005628381,0.9980652,0.00003870396,0.00002408771,0.001158546],"study_design_scores_gemma":[0.00008006504,0.001061228,0.001933342,0.0000137924,0.00002330145,0.000218488,0.00003571406,0.0004558443,0.9946569,0.00004594584,0.001471275,0.000004094358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942564,0.002552833,0.001625463,0.0001592366,0.00005952878,0.00002953137,0.0002058837,0.00007924997,0.001031898],"genre_scores_gemma":[0.9914113,0.002315687,0.00258712,0.0001130192,0.00001918596,0.00004904771,0.0005531472,0.00001438085,0.002937058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001089978,"threshold_uncertainty_score":0.003646374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006140901462655832,"score_gpt":0.2005594574364901,"score_spread":0.1944185559738343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}