{"id":"W2155005030","doi":"10.1093/carcin/bgr044","title":"Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acid","year":2011,"lang":"nl","type":"article","venue":"Carcinogenesis","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Division of Chemistry; National Heart, Lung, and Blood Institute; McGill University Health Centre; Canadian Institutes of Health Research; National Institutes of Health; National Science Foundation","keywords":"Arachidonic acid; Docosahexaenoic acid; Glutathione; Chemistry; Biochemistry; Cancer cell; Cell culture; Oxidative stress; Cytotoxic T cell; Biology; Fatty acid; Cancer; Internal medicine; Enzyme; Medicine; Polyunsaturated fatty acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007510859,0.001246631,0.001579652,0.0006705078,0.0003156834,0.00007554982,0.0009642262,0.001141745,0.0004652102],"category_scores_gemma":[0.0001992916,0.001272334,0.0003949035,0.0009189458,0.0005697469,0.0001074099,0.000695803,0.0004758429,0.00005951514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002510115,"about_ca_system_score_gemma":0.00050517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007457648,"about_ca_topic_score_gemma":0.00206008,"domain_scores_codex":[0.9931702,0.001166894,0.001665264,0.001872986,0.0005582755,0.001566392],"domain_scores_gemma":[0.9963026,0.0001087896,0.0008103963,0.001230221,0.0007472319,0.0008007452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004256056,0.0007348646,0.003171848,0.0003873922,0.0002507465,0.00007203352,0.002403191,0.00005193373,0.9836535,0.00001129834,0.002627358,0.002379779],"study_design_scores_gemma":[0.004516352,0.00174609,0.01573224,0.000220177,0.0004567288,0.00003038732,0.0008833692,0.00009788584,0.971718,0.00002199065,0.003280061,0.001296723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9726173,0.02109255,0.0004511998,0.0005914032,0.0009192712,0.001804233,0.002361784,0.00004875306,0.0001135091],"genre_scores_gemma":[0.9883615,0.008427837,0.0004444815,0.001246996,0.0002227471,0.0004064299,0.0004334539,0.0001685385,0.0002880468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01574418,"threshold_uncertainty_score":0.9989727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01751723401932917,"score_gpt":0.2506879476154796,"score_spread":0.2331707135961505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}