{"id":"W2155005693","doi":"10.1128/jvi.74.8.3781-3792.2000","title":"The IRF-3 Transcription Factor Mediates Sendai Virus-Induced Apoptosis","year":2000,"lang":"en","type":"article","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Biology; Interferon regulatory factors; Jurkat cells; Transactivation; Molecular biology; Transcription factor; DNA laddering; Cell biology; IRF1; Interferon; Apoptosis; Transfection; Programmed cell death; DNA fragmentation; Virology; Cell culture; T cell; Gene; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003791818,0.0001490695,0.0003179293,0.0001085489,0.0002360448,0.00001851834,0.0003267498,0.0002770255,0.004507245],"category_scores_gemma":[0.00009664538,0.00009005595,0.0002274688,0.00006824079,0.0002081925,0.0001180085,0.00001368584,0.00057521,0.0006299494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003427394,"about_ca_system_score_gemma":0.00006292343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002855809,"about_ca_topic_score_gemma":0.00002193913,"domain_scores_codex":[0.9983749,0.0005940674,0.0005436708,0.000108861,0.00004601629,0.0003324859],"domain_scores_gemma":[0.9991349,0.0003629522,0.0002259283,0.0001657114,0.0000839663,0.0000265327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00234171,0.00008315855,0.00006040252,0.000001900478,0.0002273796,0.000003926511,0.0005332685,0.00000131922,0.9539101,0.00006840167,0.003460614,0.03930784],"study_design_scores_gemma":[0.001211333,0.001417681,0.005567171,0.00001027997,0.00005227445,0.0004470592,0.0001696023,0.000001855482,0.7066563,0.000103914,0.284265,0.00009746836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910098,0.003880067,0.00002065234,0.002616662,0.001769332,0.00006675909,0.00001211898,0.00001475416,0.0006099022],"genre_scores_gemma":[0.994404,0.002476815,0.00001056968,0.00050918,0.0001055577,0.000002744151,0.000003633918,0.00001297096,0.002474513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2808044,"threshold_uncertainty_score":0.9964027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01438317618770082,"score_gpt":0.2480307856422239,"score_spread":0.2336476094545231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}