{"id":"W2155093913","doi":"10.1126/science.289.5482.1202","title":"Inflammation Dampened by Gelatinase A Cleavage of Monocyte Chemoattractant Protein-3","year":2000,"lang":"en","type":"article","venue":"Science","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":773,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Medical Council of Canada","funders":"","keywords":"Hemopexin; Chemotaxis; Inflammation; Matrix metalloproteinase; Gelatinase; Chemokine; Monocyte; Chemistry; Cell biology; Chemokine receptor; Gelatinase A; CXC chemokine receptors; Extracellular matrix; Receptor; CXCL2; Biochemistry; Immunology; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000277685,0.00007270875,0.00006502045,0.00002292584,0.00008269752,0.00001768318,0.0002153754,0.00004971508,0.00004618821],"category_scores_gemma":[0.00005244561,0.00006656472,0.00002803138,0.0001517498,0.000158447,0.00001712154,0.00004135774,0.0000396146,0.00001815693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001010122,"about_ca_system_score_gemma":0.00009926557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007271066,"about_ca_topic_score_gemma":0.00000138024,"domain_scores_codex":[0.9992383,0.00001489226,0.0001446284,0.0002407148,0.0001891556,0.0001723458],"domain_scores_gemma":[0.9995703,0.00000151922,0.00006349418,0.0002540475,0.00004637392,0.00006432632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000311045,0.00001869918,0.0000132285,0.000005367184,0.000001496846,5.379757e-7,0.00001911928,0.000003145518,0.9877294,0.00007199044,0.00009969035,0.01200618],"study_design_scores_gemma":[0.0001832582,0.0001711944,0.0000827425,0.00001351206,0.000001990074,0.000002660881,0.00001155637,0.000108827,0.9938178,0.0001979888,0.005322828,0.00008566384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943748,0.0001343264,0.0002829212,0.00005351878,0.00002310299,0.0002326952,0.000006682353,0.000008007332,0.004883973],"genre_scores_gemma":[0.9979107,0.00002095895,0.0008829149,0.00004493535,0.00004727258,0.00001957491,0.00001220304,0.000005390818,0.00105605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01192051,"threshold_uncertainty_score":0.2714431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004248336349921729,"score_gpt":0.2197847004758912,"score_spread":0.2155363641259695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}