{"id":"W2155107722","doi":"10.1039/c4ob00739e","title":"Synthesis of 4-methyl-N′-(3-alkyl-2r,6c-diarylpiperidin-4-ylidene)-1,2,3-thiadiazole-5-carbohydrazides with antioxidant, antitumor and antimicrobial activities","year":2014,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Antimicrobial; Alkyl; Antioxidant; Combinatorial chemistry; Organic chemistry; Medicinal chemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003369757,0.0005617167,0.0008443376,0.00005828218,0.0001868231,0.0001040476,0.0004808819,0.0004084377,0.0008725164],"category_scores_gemma":[0.0005235907,0.000452672,0.0002139263,0.0002996135,0.0007178931,0.000155764,0.000248165,0.0003136309,0.000009976467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005964477,"about_ca_system_score_gemma":0.00009629186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006399421,"about_ca_topic_score_gemma":0.000006374817,"domain_scores_codex":[0.9976346,0.00007614632,0.0004629876,0.0008704097,0.0003680056,0.000587786],"domain_scores_gemma":[0.9981458,0.0004137869,0.0003783597,0.0007482814,0.00008617533,0.0002275614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001126255,0.0002698566,0.003840925,0.0007325557,0.0001922922,0.00004231853,0.00002959269,2.314172e-7,0.9907426,0.0000201511,0.00004070228,0.003976096],"study_design_scores_gemma":[0.0004621223,0.00004113054,0.001015374,0.0003414222,0.0001826871,0.0001817395,0.0001152021,0.00005710481,0.9964076,0.00003803611,0.0005261697,0.0006313902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920467,0.0003335378,0.001629637,0.0002264911,0.0000364582,0.00008312336,0.0000870682,0.0001508097,0.005406202],"genre_scores_gemma":[0.9984549,0.0002349446,0.0007785706,0.00007864385,0.0001851184,0.00001846758,0.0000202506,0.00007850766,0.0001506378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006408186,"threshold_uncertainty_score":0.9997925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004238573336187029,"score_gpt":0.1839068221227464,"score_spread":0.1796682487865593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}