{"id":"W2155155386","doi":"10.1091/mbc.e03-02-0077","title":"The Role of Subunit Assembly in Peripherin-2 Targeting to Rod Photoreceptor Disk Membranes and Retinitis Pigmentosa","year":2003,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Eye Institute; Canadian Institutes of Health Research; National Institutes of Health; Foundation Fighting Blindness","keywords":"Peripherin; Biology; Retinitis pigmentosa; Cell biology; Mutant; Retinal degeneration; Lipid bilayer fusion; Genetics; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003420778,0.0001331458,0.0001618822,0.00002500273,0.00007032281,0.00000611833,0.0002249291,0.0001385683,0.0000158678],"category_scores_gemma":[0.00007866075,0.00009288976,0.00009812842,0.0001028219,0.0001715104,0.000001621813,0.00006877506,0.0000827827,7.274025e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006048886,"about_ca_system_score_gemma":0.0000316038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006127587,"about_ca_topic_score_gemma":0.00007182525,"domain_scores_codex":[0.9990477,0.000170586,0.0002594125,0.0002380271,0.0000732386,0.0002110382],"domain_scores_gemma":[0.9994932,0.00001870452,0.000109103,0.0002935096,0.00004259705,0.00004290486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000056321,0.00003261192,0.01383139,0.00001927456,0.00001812044,7.466139e-7,0.0001212215,0.00002203076,0.9853634,0.0002218953,0.000005797208,0.0003072355],"study_design_scores_gemma":[0.0002759364,0.0001435326,0.001113443,0.0000102886,0.00001413029,0.000002481023,0.0002761538,0.0000128001,0.9526651,0.000189038,0.04519285,0.0001042777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920644,0.005398843,0.0005492478,0.00008454677,0.00009818532,0.0002387386,0.00001187976,0.000002687358,0.001551464],"genre_scores_gemma":[0.9989589,0.0004131066,0.0002941016,0.00005190964,0.00001409684,0.00001454504,0.00009429051,0.00001529866,0.0001436969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04518705,"threshold_uncertainty_score":0.3787934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003098547638484355,"score_gpt":0.199139457129355,"score_spread":0.1960409094908707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}