{"id":"W2155157530","doi":"10.1158/0008-5472.can-09-4676","title":"Oncogenic Ras Promotes Reovirus Spread by Suppressing IFN-β Production through Negative Regulation of <i>RIG-I</i> Signaling","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Transfection; Interferon; Viral replication; RIG-I; Virology; Virus; Signal transduction; Cell culture; RNA; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009976798,0.0003723,0.0001942045,0.0002197218,0.0001082481,0.0003018274,0.0001404204,0.0001563631,0.001239302],"category_scores_gemma":[0.00007893033,0.000105114,0.0002520478,0.00008284886,0.0001877999,0.0001605187,0.0001597368,0.000522126,0.0004133171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001680521,"about_ca_system_score_gemma":0.0002026043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004279689,"about_ca_topic_score_gemma":0.0005668841,"domain_scores_codex":[0.9998863,0.00002143021,0.0000121458,0.00001523986,0.00003283473,0.00003204899],"domain_scores_gemma":[0.9999219,0.00001487876,0.00002095188,0.00001406701,0.000008772528,0.00001927388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008094636,0.00002304882,0.000108359,0.00001211574,0.000002327355,0.00002031878,0.000006537695,0.00003155521,0.9986539,0.00006233112,0.00001523878,0.0009833131],"study_design_scores_gemma":[0.00001114789,0.0001955539,0.001830081,0.000002938671,0.000008966258,0.000150614,0.00001335106,0.0006053919,0.9961343,0.00003490532,0.001010906,0.000001840212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949832,0.0008532886,0.001650149,0.00006989326,0.00001768662,0.00001602148,0.0001129673,0.0001349143,0.002161793],"genre_scores_gemma":[0.9971258,0.0004679943,0.001016972,0.00001633644,0.000004535731,0.00001003065,0.0001229026,0.00001500853,0.001220361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001239302,"threshold_uncertainty_score":0.004145861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05293381893738741,"score_gpt":0.3764663084416977,"score_spread":0.3235324895043102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}