{"id":"W2155229125","doi":"10.1186/1477-7827-4-52","title":"Activin B can signal through both ALK4 and ALK7 in gonadotrope cells","year":2006,"lang":"en","type":"article","venue":"Reproductive Biology and Endocrinology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Activin receptor; ACVR2B; Activin type 2 receptors; Transfection; Biology; Molecular biology; Gonadotropic cell; Receptor; Endocrinology; Smad2 Protein; Internal medicine; Signal transduction; TGF beta signaling pathway; Cell biology; Transforming growth factor beta; Pituitary gland; Cell culture; Transforming growth factor; Medicine; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000133893,0.0003529953,0.0001335831,0.0002477872,0.0001987995,0.0003721414,0.0001773082,0.0002616155,0.002992487],"category_scores_gemma":[0.0001090419,0.0001870961,0.0003317284,0.0001657749,0.0002356464,0.0001874614,0.0002182768,0.0005528168,0.001411403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003097322,"about_ca_system_score_gemma":0.000282532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007207714,"about_ca_topic_score_gemma":0.00127831,"domain_scores_codex":[0.9998909,0.0000103896,0.00001094879,0.00001831375,0.00003871789,0.00003066222],"domain_scores_gemma":[0.9998567,0.00002403343,0.00004052473,0.0000157782,0.00002248582,0.00004045838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000718048,0.000009558912,0.0003404422,0.00002015652,0.000003648323,0.0000423511,0.000006249654,0.00001751245,0.9990203,0.00006664028,0.00003017074,0.0003711649],"study_design_scores_gemma":[0.00004885031,0.0002317296,0.009391196,0.000008306315,0.00003105449,0.0005095628,0.00007683782,0.0006899238,0.9827577,0.00006518448,0.006183102,0.000006500157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918914,0.00143399,0.002561262,0.0001942899,0.00004951537,0.00002939461,0.001104433,0.00007764118,0.002658047],"genre_scores_gemma":[0.9823037,0.001252233,0.003621101,0.0001556666,0.00004121877,0.00006723509,0.004329964,0.00006381933,0.008165076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002992487,"threshold_uncertainty_score":0.01001084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008737249095614703,"score_gpt":0.2516688914856087,"score_spread":0.242931642389994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}