{"id":"W2155286781","doi":"10.1038/ng1104-1133","title":"The Collaborative Cross, a community resource for the genetic analysis of complex traits","year":2004,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Genetic Mapping and Diversity in Plants and Animals","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1193,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Centre for Phenogenomics; University of Toronto; McGill University; Montreal Clinical Research Institute; Mount Sinai Hospital","funders":"Oak Ridge National Laboratory; National Heart, Lung, and Blood Institute; Medical Research Council; University of North Carolina at Chapel Hill; Health Science Center, University of Tennessee; University of California, Los Angeles; School of Medicine, Emory University; School of Medicine, New York University; National Institutes of Health; International Livestock Research Institute; National Institute on Alcohol Abuse and Alcoholism; Akademie Věd České Republiky; Rijksuniversiteit Groningen; National Cancer Institute; Universität Heidelberg; Vanderbilt University Medical Center; Cedars-Sinai Medical Center; Purdue University; Wellcome Trust; University of Cincinnati; David Geffen School of Medicine, University of California, Los Angeles; Medical Center, University of Rochester; Case Western Reserve University; Emory University; Northwestern University; University of Rochester; Johns Hopkins University; Advanced Scientific Computing Research; University of Wisconsin-Madison; Cincinnati Children's Hospital Medical Center; University at Buffalo; Helsingin Yliopisto; College of Medicine, University of Cincinnati; Shriners Hospitals for Children; McGill University; University of Pennsylvania; Hebrew University of Jerusalem; University of Toronto; Yale University; Vanderbilt University; University of Memphis; Thomas Jefferson University","keywords":"Biology; Trait; Complex disease; Resource (disambiguation); Computational biology; Genetic resources; Quantitative trait locus; Gene; Genetics; Data science; Biotechnology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003977241,0.0009610728,0.001286471,0.007683644,0.002522132,0.001728285,0.002650968,0.0009307403,0.05837528],"category_scores_gemma":[0.007322009,0.0007416388,0.0004937928,0.007576083,0.000488378,0.001468269,0.004365908,0.00177533,0.01338517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005757712,"about_ca_system_score_gemma":0.004238501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008461483,"about_ca_topic_score_gemma":0.02652191,"domain_scores_codex":[0.9983578,0.0004181309,0.00009085816,0.0002607042,0.0006820448,0.0001904859],"domain_scores_gemma":[0.9883149,0.002393862,0.0006760865,0.003731029,0.001215418,0.003668844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001596386,0.0009858459,0.01248567,0.0008299288,0.0003113527,0.00168239,0.001669909,0.001033344,0.08283462,0.0187858,0.4138685,0.4639163],"study_design_scores_gemma":[0.001009341,0.0004459168,0.05053115,0.0002781424,0.0003558758,0.003639267,0.0005234668,0.003327443,0.02419372,0.01579574,0.899621,0.0002790362],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1562938,0.005583967,0.387682,0.003663305,0.001571465,0.002814227,0.2068409,0.0315689,0.2039815],"genre_scores_gemma":[0.1491773,0.003609441,0.4784417,0.00101169,0.0006229409,0.003122753,0.2451905,0.01095958,0.1078641],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.05837528,"threshold_uncertainty_score":0.1952848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741388490512984,"score_gpt":0.2863049274175402,"score_spread":0.2688910425124103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}