{"id":"W2155301516","doi":"10.1093/jac/dkn250","title":"Efficacy and safety of tigecycline compared with vancomycin or linezolid for treatment of serious infections with methicillin-resistant Staphylococcus aureus or vancomycin-resistant enterococci: a Phase 3, multicentre, double-blind, randomized study","year":2008,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Tigecycline; Medicine; Linezolid; Vancomycin; Methicillin-resistant Staphylococcus aureus; Population; Internal medicine; Surgery; Enterococcus faecium; Vancomycin-resistant Enterococcus; Staphylococcus aureus; Antibiotics; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003284805,0.001694527,0.00298824,0.0005345244,0.0005409732,0.001166441,0.001169976,0.002417667,0.003691146],"category_scores_gemma":[0.003560239,0.0008333887,0.002828154,0.0004654193,0.001479015,0.001009559,0.0003838229,0.003084699,0.000575328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009075319,"about_ca_system_score_gemma":0.001827953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008475104,"about_ca_topic_score_gemma":0.001901303,"domain_scores_codex":[0.9979881,0.001348236,0.0001480327,0.000207682,0.0001495086,0.0001584201],"domain_scores_gemma":[0.9966218,0.001267515,0.0009998998,0.0002239469,0.0001999157,0.0006868162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9768822,0.00999294,0.0004757291,0.0004418851,0.000638492,0.00002113588,0.00004968699,0.0001897512,0.002631147,0.00003511061,0.0002200909,0.008421788],"study_design_scores_gemma":[0.8546144,0.1422797,0.001700891,0.00002976871,0.0003112347,0.00002407926,0.00001375018,0.0003637725,0.0004665971,0.00004754259,0.0001353111,0.00001282575],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937621,0.002450537,0.0004801943,0.0002447562,0.000250356,0.001977225,0.0003150381,0.00005291387,0.0004669149],"genre_scores_gemma":[0.9915327,0.001948332,0.001384343,0.0005591892,0.0004179312,0.002980206,0.0004424,0.0000218098,0.0007130039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003691146,"threshold_uncertainty_score":0.01737189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04193161740394345,"score_gpt":0.3426745796557364,"score_spread":0.3007429622517929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}