{"id":"W2155327121","doi":"10.1242/dev.076760","title":"Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis","year":2012,"lang":"en","type":"article","venue":"Development","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; Ribosome biogenesis; stat; Cell biology; Carcinogenesis; Biogenesis; Ribosome; Signal transduction; Genetics; RNA; Cancer; STAT3; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001276708,0.000130909,0.0001388307,0.00007268904,0.00009224153,0.00001554594,0.00005863654,0.00008330312,0.000008459123],"category_scores_gemma":[0.0000279901,0.0001204737,0.00001962566,0.00007250146,0.00007136563,0.00001075964,0.0001040353,0.00005822217,0.000001845367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001149609,"about_ca_system_score_gemma":0.00005438185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002540884,"about_ca_topic_score_gemma":0.00001330715,"domain_scores_codex":[0.9992953,0.00004239149,0.0001826364,0.0001931994,0.00009779786,0.0001886529],"domain_scores_gemma":[0.9996439,0.00002239599,0.00008252804,0.00008671318,0.0000640787,0.0001003973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003378127,0.00006800629,0.02464175,0.0000270014,0.0001053772,6.282498e-7,0.001057677,5.516983e-7,0.9720681,0.0001142179,0.00001014105,0.001872752],"study_design_scores_gemma":[0.000240067,0.00004161097,0.06542682,0.00004224212,0.00001231279,0.00001315026,0.0006140816,6.971019e-7,0.9309176,0.00001571134,0.002529391,0.0001463421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986972,0.0006068463,0.00008135402,0.00003719995,0.00009694042,0.00008922858,0.00002226127,0.00000961293,0.0003593572],"genre_scores_gemma":[0.9982523,0.0001156383,0.001316004,0.00003738875,0.00005034213,0.00001306244,0.00009839667,0.0000132445,0.0001036696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04115054,"threshold_uncertainty_score":0.4912776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01614641003458684,"score_gpt":0.2383857573422832,"score_spread":0.2222393473076963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}