{"id":"W2155433991","doi":"10.1186/2051-5960-2-16","title":"Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury","year":2014,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Anesthesia and Neurotoxicity Research","field":"Neuroscience","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences","keywords":"Wallerian degeneration; Neurodegeneration; Biology; Neuroscience; Axon; Neurite; Degeneration (medical); Cell biology; Pathology; Medicine; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003982763,0.0001316705,0.0002400353,0.0001371679,0.0001950321,0.0000247405,0.0002611911,0.00008278352,0.000002071483],"category_scores_gemma":[0.0007295186,0.0001159716,0.0000173073,0.0002505628,0.0005712887,0.0001153362,0.0004759058,0.0003755932,8.618019e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007436607,"about_ca_system_score_gemma":0.00002296953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001102401,"about_ca_topic_score_gemma":0.00003112437,"domain_scores_codex":[0.9979967,0.00112698,0.0002673871,0.0002883644,0.0001598075,0.0001607748],"domain_scores_gemma":[0.9979578,0.001290499,0.000149288,0.0004908352,0.00004215929,0.0000694004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001198693,0.0001257593,0.0311337,0.00002175161,0.000001171296,0.00001849278,0.0008748203,4.128293e-7,0.9632228,0.0002244884,0.00004193433,0.00421479],"study_design_scores_gemma":[0.0003308426,0.0002626395,0.5012769,0.00002511887,0.000006686758,0.0001961714,0.00008742102,0.003574578,0.4935038,0.00003171105,0.0005815352,0.0001225887],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963414,0.00005423931,0.000005397446,0.002949668,0.000006743079,0.0003105853,0.00001989759,0.00001686301,0.0002951937],"genre_scores_gemma":[0.9978604,0.0005760633,0.0006349839,0.0008584739,0.000003738773,0.0000218996,0.00000791417,0.00001089199,0.00002558313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4701432,"threshold_uncertainty_score":0.4729185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04930162796505845,"score_gpt":0.29962117823303,"score_spread":0.2503195502679715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}