{"id":"W2155443081","doi":"10.1016/j.cub.2012.08.024","title":"A Genome-wide Functional Screen Shows MAGI-1 Is an L1CAM-Dependent Stabilizer of Apical Junctions in C. elegans","year":2012,"lang":"en","type":"article","venue":"Current Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institutes of Health; American Cancer Society","keywords":"Biology; Cell biology; Morphogenesis; Actin; Cadherin; FERM domain; PDZ domain; L1; Actin cytoskeleton; Cytoskeleton; Cell junction; Cell polarity; Membrane protein; Genetics; Cell; Gene; Integral membrane protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002172575,0.0001559755,0.0001817821,0.0001061023,0.00005142462,0.000007288247,0.0001446957,0.0001750865,0.0009816713],"category_scores_gemma":[0.00005344072,0.0001446476,0.0001197781,0.00009272158,0.00007630786,0.00001324225,0.0001183609,0.000196676,0.00003807476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003251242,"about_ca_system_score_gemma":0.00006456921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004008793,"about_ca_topic_score_gemma":0.0001470551,"domain_scores_codex":[0.9988159,0.0001100929,0.0003223765,0.0003293886,0.00008051082,0.0003417087],"domain_scores_gemma":[0.9993489,0.00001652231,0.00008981617,0.0003200016,0.00009235105,0.0001324292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001209438,0.0009018247,0.1029159,0.00001378513,0.00005552985,2.956407e-7,0.00008936862,0.000006667273,0.8892713,0.002157746,0.001458967,0.003007609],"study_design_scores_gemma":[0.00162248,0.001020504,0.1133704,0.00001937391,0.00007870508,0.00004176421,0.0003208701,0.0002319486,0.2037872,0.00082788,0.6780289,0.0006499315],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756694,0.002426656,0.01907274,0.0001365045,0.001519096,0.0002083139,0.0001869589,0.00001048423,0.0007698478],"genre_scores_gemma":[0.9975829,0.0002925415,0.0001564878,0.0001367839,0.000424415,0.00003612193,0.0009216237,0.0000164714,0.0004327263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6854841,"threshold_uncertainty_score":0.9999316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04147155762847463,"score_gpt":0.2975989433264983,"score_spread":0.2561273856980236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}