{"id":"W2155443081","doi":"10.1016/j.cub.2012.08.024","title":"A Genome-wide Functional Screen Shows MAGI-1 Is an L1CAM-Dependent Stabilizer of Apical Junctions in C. elegans","year":2012,"lang":"en","type":"article","venue":"Current Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institutes of Health; American Cancer Society","keywords":"Biology; Cell biology; Morphogenesis; Actin; Cadherin; FERM domain; PDZ domain; L1; Actin cytoskeleton; Cytoskeleton; Cell junction; Cell polarity; Membrane protein; Genetics; Cell; Gene; Integral membrane protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002556337,0.0007161935,0.00045651,0.0006719746,0.0005696852,0.0005694214,0.000673264,0.000746078,0.002122548],"category_scores_gemma":[0.0002012594,0.0003383495,0.0004689757,0.000278661,0.0004278859,0.000172181,0.0004677773,0.0008481079,0.0008428728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006033533,"about_ca_system_score_gemma":0.000341582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001946224,"about_ca_topic_score_gemma":0.005838931,"domain_scores_codex":[0.9997486,0.00001916727,0.0000196499,0.00007574314,0.00009886694,0.00003783534],"domain_scores_gemma":[0.9997378,0.0000515739,0.00008951664,0.00002409813,0.00002154705,0.00007548517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000511138,0.0000170093,0.0002131202,0.00002879089,0.00001088461,0.00008854467,0.000006012103,0.0000962937,0.9985347,0.00007504626,0.00008513204,0.0007934695],"study_design_scores_gemma":[0.0000565216,0.000227927,0.02158346,0.00001677266,0.0001448157,0.0006177413,0.00006284535,0.004202243,0.9687619,0.0001078284,0.004190592,0.00002743058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884136,0.001092227,0.004211927,0.0002629104,0.00007161794,0.00005978838,0.003025126,0.0003826867,0.002480157],"genre_scores_gemma":[0.9915736,0.000438784,0.002637583,0.0001731475,0.000009244539,0.00003541824,0.001870328,0.0000951895,0.003166693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002122548,"threshold_uncertainty_score":0.007100642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04147155762847463,"score_gpt":0.2975989433264983,"score_spread":0.2561273856980236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}