{"id":"W2155450712","doi":"10.1016/j.cardiores.2004.03.010","title":"Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-β1 involves furin-convertase","year":2004,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Bundesministerium für Bildung und Forschung; National Institutes of Health; Deutscher Akademischer Austauschdienst","keywords":"Furin; Matrix metalloproteinase; Metalloproteinase; Cell biology; Transforming growth factor; Fibroblast; Cancer research; Proprotein convertase; Chemistry; Medicine; Biology; Internal medicine; Enzyme; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000152444,0.0004729295,0.0001626157,0.0001639514,0.0001371188,0.0002162744,0.00009156478,0.0001907388,0.001007486],"category_scores_gemma":[0.00009146687,0.00009632601,0.000229333,0.00008658109,0.0001703218,0.000204776,0.0001094899,0.0003516421,0.0002569763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001820935,"about_ca_system_score_gemma":0.0001086474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003350609,"about_ca_topic_score_gemma":0.0003212555,"domain_scores_codex":[0.9999003,0.00001876809,0.00001135074,0.00002070635,0.00002348049,0.00002533151],"domain_scores_gemma":[0.9999152,0.00001645232,0.00003087712,0.000005142075,0.00001491204,0.00001733595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001660141,0.0000331906,0.0003660982,0.00005537481,0.000003285287,0.00006864089,0.00001863904,0.00001406246,0.9981251,0.00002997578,0.00001496844,0.00110463],"study_design_scores_gemma":[0.00004119287,0.0006746434,0.02048377,0.00001775398,0.00002225536,0.0005762977,0.0000593002,0.0005697931,0.9756536,0.00005791459,0.001839043,0.000004574664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871702,0.008409262,0.002746877,0.0001303231,0.00003596471,0.00004001718,0.0002115847,0.00003820709,0.001217541],"genre_scores_gemma":[0.9930997,0.003173194,0.00210657,0.00003144345,0.00001973994,0.0000461145,0.0001626765,0.000004064282,0.001356469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001007486,"threshold_uncertainty_score":0.003370404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03658452252069,"score_gpt":0.3283035602429699,"score_spread":0.2917190377222799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}