{"id":"W2155477306","doi":"10.1182/blood-2011-03-278127","title":"How I treat hemophagocytic lymphohistiocytosis","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":1138,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institutes of Health; National Heart, Lung, and Blood Institute; Cincinnati Children's Hospital Medical Center; American Society of Hematology","keywords":"Hemophagocytic lymphohistiocytosis; Medicine; Disease; Macrophage activation syndrome; Immunology; Immune dysregulation; Immune system; Pediatrics; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007624638,0.0001122385,0.0002235775,0.00009380656,0.00006962831,0.00001858021,0.00009517001,0.00007537654,0.0005132194],"category_scores_gemma":[0.00007764692,0.00009199653,0.00009875594,0.0001445834,0.00007971463,0.00009297258,0.00003724277,0.00009384626,0.0002546877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003157197,"about_ca_system_score_gemma":0.0001437858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004883508,"about_ca_topic_score_gemma":0.00000194112,"domain_scores_codex":[0.9991977,0.00002026909,0.0001304328,0.0001817718,0.0002087744,0.0002610156],"domain_scores_gemma":[0.9994273,0.00001231595,0.0000336829,0.0003499537,0.00006239228,0.0001143099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001376091,0.01085261,0.6360527,0.001450366,0.001493341,0.003799158,0.006475531,3.159604e-7,0.155198,0.00538172,0.01452077,0.1633994],"study_design_scores_gemma":[0.02301378,0.001448509,0.2764832,0.0001535222,0.0008539862,0.0007823114,0.001345374,0.0000898704,0.6592492,0.0004310433,0.03554631,0.0006029389],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.90989,0.001715563,0.00004692307,0.0002635522,0.00003380373,0.0002153259,0.000002323741,0.000107006,0.0877255],"genre_scores_gemma":[0.9855285,0.0001404706,0.0004012705,0.0001416586,0.00005681812,0.00002983402,0.000007828287,0.00002326377,0.01367039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5040512,"threshold_uncertainty_score":0.5619393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0381820793013617,"score_gpt":0.2534675904848563,"score_spread":0.2152855111834946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}