{"id":"W2155491988","doi":"10.1080/713608373","title":"A Framework for Human Relevance Analysis of Information on Carcinogenic Modes of Action","year":2003,"lang":"en","type":"review","venue":"Critical Reviews in Toxicology","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":442,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Comparability; Relevance (law); Risk assessment; Animal testing; Risk analysis (engineering); Human studies; Medicine; Computer science; Toxicology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000688772,0.0002849043,0.002189604,0.0004016561,0.00003561575,0.000007122244,0.000232256,0.0007226351,0.00003978014],"category_scores_gemma":[0.002090745,0.0002507387,0.00111547,0.0005150472,0.0001505322,0.000005472779,0.00005817895,0.0002489969,0.00000238753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009965387,"about_ca_system_score_gemma":0.0001352195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005425315,"about_ca_topic_score_gemma":0.00006139868,"domain_scores_codex":[0.9974723,0.0004000209,0.001377075,0.0003542089,0.000122642,0.0002736948],"domain_scores_gemma":[0.9983341,0.0003952145,0.0005039894,0.000575763,0.0001290756,0.00006184865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006739152,0.0004683085,0.00002961446,0.03770695,0.0008247214,0.000001072291,0.00003071415,0.00007405531,0.004438902,0.09280524,0.0002685843,0.8632845],"study_design_scores_gemma":[0.0001689732,0.0008832247,0.00002597419,0.002600086,0.002973006,0.000003753392,0.00001616452,0.00002385731,0.002212935,0.00138743,0.9894134,0.0002911735],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007424647,0.9811043,0.01633599,0.00001396264,0.0001300008,0.001291501,0.0002021895,0.000002398653,0.000177257],"genre_scores_gemma":[0.00611744,0.988816,0.00392254,0.0001427883,0.00005089615,0.0005095863,0.0004058767,0.00001719374,0.00001774218],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9891449,"threshold_uncertainty_score":0.9999945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1264306380210626,"score_gpt":0.4728438992751504,"score_spread":0.3464132612540878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}