{"id":"W2155582980","doi":"10.1101/gr.137224.112","title":"Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus","year":2012,"lang":"en","type":"article","venue":"Genome Research","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Naito Foundation","keywords":"Piwi-interacting RNA; Biology; Retrotransposon; Transposable element; Gene silencing; Genetics; Gene; Homologous recombination; RNA interference; RNA; Cell biology; Genome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002794035,0.0003869352,0.0002136615,0.0003303435,0.0001608635,0.0003088515,0.0003872697,0.0003189681,0.001220966],"category_scores_gemma":[0.0001887481,0.000277877,0.000345221,0.0001435203,0.0004133945,0.0002444774,0.0003110369,0.0008013674,0.0005141944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002344021,"about_ca_system_score_gemma":0.0002143318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002686449,"about_ca_topic_score_gemma":0.0003586072,"domain_scores_codex":[0.9998016,0.00003263535,0.00002169162,0.00006703431,0.00004609011,0.00003093137],"domain_scores_gemma":[0.9998047,0.00003132385,0.00007002242,0.00004060808,0.00001183367,0.00004154289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002458572,0.000009637332,0.00005839123,0.00001369963,0.000002216096,0.00003635822,0.00001031957,0.00002100098,0.999176,0.0001432586,0.000006454151,0.0004981133],"study_design_scores_gemma":[0.0000177697,0.0002164502,0.0007722024,0.000004343959,0.00001146665,0.0001705642,0.000009617323,0.0003589833,0.9968799,0.00005841221,0.001497962,0.000002254364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728782,0.001008839,0.02341115,0.00009620334,0.00005035589,0.00009726543,0.0004076961,0.0003575131,0.001692764],"genre_scores_gemma":[0.9756706,0.0008369744,0.01676448,0.00006602283,0.00001825972,0.0001141284,0.0008832105,0.0001444554,0.005501937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001220966,"threshold_uncertainty_score":0.004084527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03743429295819898,"score_gpt":0.2781656286736807,"score_spread":0.2407313357154817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}