{"id":"W2155625237","doi":"10.1086/421503","title":"Inactivation of<i>Plasmodium falciparum</i>by Photodynamic Excitation of Heme‐Cycle Intermediates Derived from δ‐Aminolevulinic Acid","year":2004,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Malaria Research and Control","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Department of Medicine, University of Toronto; University of Toronto; Canadian Blood Services","keywords":"Plasmodium falciparum; Malaria; Heme; Biology; Hemozoin; Hemoglobin; Photodynamic therapy; Plasmodium (life cycle); Biochemistry; Chemistry; Immunology; Parasite hosting; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002317998,0.0001210368,0.0003769294,0.0001658024,0.00004999817,0.0000109722,0.0001441359,0.00005480565,0.0001163892],"category_scores_gemma":[0.0007842102,0.00008098564,0.0001832403,0.0001747941,0.0001500755,0.0001852947,0.00002755209,0.0002206215,0.00000571738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001296542,"about_ca_system_score_gemma":0.0002953154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003432302,"about_ca_topic_score_gemma":0.00004353969,"domain_scores_codex":[0.9986669,0.0001366558,0.0005384082,0.00008215541,0.0004141486,0.0001617179],"domain_scores_gemma":[0.998262,0.0003506179,0.0006447593,0.0001801755,0.0004191489,0.0001432514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003465654,0.0009909226,0.01327725,0.0001127632,0.0005212121,0.00001202061,0.00061391,0.0003998411,0.9779637,0.00005699193,0.0001522007,0.002433554],"study_design_scores_gemma":[0.01264495,0.003284413,0.4624744,0.0005739775,0.000919604,0.00007328419,0.0009233813,0.0004739334,0.5108714,0.007583617,0.00001912606,0.0001579919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947901,0.001129759,0.002892388,0.0005966583,0.0001252455,0.0002536066,0.00006132203,0.00001331633,0.0001375449],"genre_scores_gemma":[0.9992293,0.0004564336,0.00003920315,0.0001053489,0.0001156634,0.000006900292,0.0000230905,0.00001404357,0.00001002381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4670923,"threshold_uncertainty_score":0.3302498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00757337337438292,"score_gpt":0.2617154659453354,"score_spread":0.2541420925709525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}