{"id":"W2155646751","doi":"10.1177/0897190005282397","title":"Pharmacokinetics and Pharmacodynamics of the New Quinolones","year":2005,"lang":"en","type":"article","venue":"Journal of Pharmacy Practice","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Moxifloxacin; Gatifloxacin; Gemifloxacin; Medicine; Levofloxacin; Pharmacodynamics; Quinolone; Pharmacokinetics; Pharmacology; Ciprofloxacin; Respiratory tract infections; Antibiotics; Drug; Bioavailability; Intensive care medicine; Respiratory system; Internal medicine; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005115985,0.0001851616,0.0003604535,0.0001362061,0.00006619826,0.00002623184,0.0002561765,0.00004016848,0.0001800556],"category_scores_gemma":[0.0004800989,0.0001264778,0.0001905492,0.0002835448,0.0001388575,0.0004223876,0.0001182462,0.0007323652,0.000007852418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004809436,"about_ca_system_score_gemma":0.0003457977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001330358,"about_ca_topic_score_gemma":5.57042e-7,"domain_scores_codex":[0.9981985,0.0001143063,0.0007613294,0.0001351668,0.0005620634,0.0002286414],"domain_scores_gemma":[0.9975682,0.0003275255,0.001058241,0.0001786312,0.0005540281,0.0003134058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003864715,0.001479225,0.005690055,0.0002570959,0.0009729492,0.0001400769,0.001088514,0.001185852,0.8037605,0.0004574168,0.04877061,0.132333],"study_design_scores_gemma":[0.01097179,0.0002187632,0.002607838,0.0001130697,0.002621137,0.003745376,0.0001323771,0.01035192,0.2070936,0.00002986004,0.7619534,0.000160895],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9020832,0.008363759,0.001153743,0.08296329,0.001231333,0.0003847121,0.000008915468,0.00001825045,0.00379277],"genre_scores_gemma":[0.9763745,0.009091767,0.008447255,0.004001264,0.001418882,2.162749e-7,6.375475e-7,0.00003081709,0.0006346351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7131828,"threshold_uncertainty_score":0.5157613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02252066741250658,"score_gpt":0.3624991719460361,"score_spread":0.3399785045335296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}