{"id":"W2155670103","doi":"10.1371/journal.pone.0019642","title":"Polymorphisms in Stromal Genes and Susceptibility to Serous Epithelial Ovarian Cancer: A Report from the Ovarian Cancer Association Consortium","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Simon Fraser University; BC Cancer Agency; CARE Canada; Alberta Health Services","funders":"National Cancer Institute; Canadian Institutes of Health Research; Cancer Research UK; WorkSafe Victoria; Lon V. Smith Foundation; National Institute for Health and Care Research; Bundesministerium für Bildung und Forschung; Michael Smith Health Research BC; Helsingin ja Uudenmaan Sairaanhoitopiiri; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Fondation pour la Recherche Médicale; Universität Ulm; Medizinischen Hochschule Hannover; Kræftens Bekæmpelse; Mayo Foundation for Medical Education and Research; U.S. Department of Defense","keywords":"Ovarian cancer; Serous fluid; Stromal cell; Lumican; Biology; Odds ratio; Colorectal cancer; Carcinogenesis; Cancer; Oncology; Bioinformatics; Internal medicine; Genetics; Medicine; Cancer research; Decorin; Extracellular matrix","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005359134,0.0005338686,0.0007501478,0.001628021,0.0009048967,0.001663547,0.0005954694,0.001018148,0.001699085],"category_scores_gemma":[0.01218795,0.0003473224,0.001509383,0.004156417,0.0005775256,0.0002655453,0.001320911,0.0008524188,0.0001704448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005736757,"about_ca_system_score_gemma":0.001378871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02253487,"about_ca_topic_score_gemma":0.01556746,"domain_scores_codex":[0.9960858,0.001338001,0.0005557155,0.001024416,0.0007505677,0.0002454823],"domain_scores_gemma":[0.9882771,0.004418023,0.003003295,0.001339497,0.001949334,0.001012732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008137233,0.00002617897,0.9875187,0.0001968207,0.002435284,0.0006065855,0.0002521351,0.0001119403,0.0009190353,0.0001062333,0.001825952,0.005187298],"study_design_scores_gemma":[0.0002023883,0.00006530367,0.9925064,0.0001017668,0.002062333,0.00103496,0.0002357867,0.0001879538,0.0002846531,0.0001363259,0.00315882,0.00002326119],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9685165,0.01873135,0.001568057,0.002843075,0.0001991645,0.0001205756,0.005587642,0.0000495453,0.002384],"genre_scores_gemma":[0.9906622,0.003741148,0.0008337991,0.0006569708,0.0002020603,0.0001297592,0.003263055,0.00002127185,0.0004896872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02253487,"threshold_uncertainty_score":0.04480743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03567967744431216,"score_gpt":0.2482789040280581,"score_spread":0.2125992265837459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}