{"id":"W2155706673","doi":"10.1139/o09-156","title":"Residue patterning in helix interiorsThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular &amp; Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.","year":2010,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Helix (gastropod); Protein folding; Residue (chemistry); Amphiphile; Chemistry; Folding (DSP implementation); Polar; Protein structure; Biophysics; Molecular dynamics; Crystallography; Stereochemistry; Biology; Biochemistry; Physics; Computational chemistry; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005477173,0.0003819084,0.0006103963,0.001570384,0.0006176688,0.00111363,0.0002756347,0.0003949111,0.006511264],"category_scores_gemma":[0.002647379,0.0001309114,0.0004958216,0.002979014,0.0004317782,0.0006758567,0.0006715901,0.0006005805,0.00382005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002538421,"about_ca_system_score_gemma":0.0004461324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000600349,"about_ca_topic_score_gemma":0.002317171,"domain_scores_codex":[0.9992375,0.0001020413,0.00009430044,0.0002675692,0.0002079033,0.00009065551],"domain_scores_gemma":[0.9978544,0.0006864773,0.0007199204,0.0003092177,0.0002318678,0.0001980747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002426852,0.0002279665,0.4436122,0.004080912,0.0006326849,0.001836461,0.0007507629,0.003744412,0.1116407,0.003518204,0.1343393,0.2931896],"study_design_scores_gemma":[0.0000668903,0.0003797013,0.6802103,0.0005244202,0.0004509319,0.003456163,0.0006473724,0.007986474,0.02293399,0.00613176,0.2770731,0.0001388216],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.871759,0.01993332,0.01053194,0.00134387,0.002181333,0.00006599675,0.0828006,0.001610093,0.009773791],"genre_scores_gemma":[0.8728477,0.006629283,0.01442139,0.0004530863,0.0006569227,0.00006381773,0.0982087,0.0005016234,0.006217562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006511264,"threshold_uncertainty_score":0.0217824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007049280544655346,"score_gpt":0.2307008220472789,"score_spread":0.2236515415026236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}