{"id":"W2155777530","doi":"10.1016/j.ejca.2011.04.030","title":"Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: Final results of a randomised phase III study (EORTC 18032)","year":2011,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":210,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Dacarbazine; Temozolomide; Medicine; Nausea; Phases of clinical research; Adverse effect; Clinical endpoint; Internal medicine; Oncology; Chemotherapy; Surgery; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001745394,0.0002193649,0.0006720191,0.0004271966,0.00003986126,0.00001333972,0.0002026408,0.00003074741,0.0006343825],"category_scores_gemma":[0.0002707507,0.0001740752,0.0001883819,0.0003456195,0.00007435595,0.00009283124,0.00006602611,0.0004309912,0.00001353402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000138538,"about_ca_system_score_gemma":0.0001466202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001023399,"about_ca_topic_score_gemma":0.0001212866,"domain_scores_codex":[0.9971997,0.0004624616,0.001364669,0.0002453146,0.0004726441,0.0002552154],"domain_scores_gemma":[0.9982197,0.00006946847,0.0008841,0.0003271219,0.000281597,0.0002180504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8775952,0.005490726,0.00190147,0.00009469198,0.001651502,0.02057713,0.005965929,0.0001104904,0.01812651,0.00002600774,0.002248886,0.06621148],"study_design_scores_gemma":[0.8611383,0.01642077,0.09538477,0.0004441297,0.001048368,0.0003150415,0.002893524,0.0003221876,0.006690969,0.00000492796,0.01497483,0.0003621671],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732952,0.0005367622,0.00007884991,0.0001231278,0.0007402488,0.0007757115,0.00001367066,0.00002291707,0.02441353],"genre_scores_gemma":[0.9959835,0.0001731514,0.0003367546,0.00006212264,0.0002182512,0.000006222331,0.000003129207,0.00003983797,0.003177002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0934833,"threshold_uncertainty_score":0.7098582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05815835894789728,"score_gpt":0.3220258166822701,"score_spread":0.2638674577343729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}