{"id":"W2155777530","doi":"10.1016/j.ejca.2011.04.030","title":"Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: Final results of a randomised phase III study (EORTC 18032)","year":2011,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":210,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Dacarbazine; Temozolomide; Medicine; Nausea; Phases of clinical research; Adverse effect; Clinical endpoint; Internal medicine; Oncology; Chemotherapy; Surgery; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001988996,0.00130393,0.002585422,0.0004753436,0.0003031164,0.00082646,0.001095732,0.001121482,0.00510401],"category_scores_gemma":[0.001565511,0.0006302176,0.001495222,0.000551417,0.001035082,0.001087506,0.0004293695,0.003090843,0.0007641991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001152872,"about_ca_system_score_gemma":0.001071333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002248703,"about_ca_topic_score_gemma":0.005168153,"domain_scores_codex":[0.9993829,0.0003497727,0.00002453029,0.00009078905,0.00004052221,0.0001115143],"domain_scores_gemma":[0.9991093,0.0002471553,0.0001550198,0.0000997992,0.00003043242,0.0003581788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9525684,0.009901049,0.0009107235,0.0003782282,0.000756579,0.00003460115,0.000116984,0.001440452,0.005519284,0.00009313063,0.0008408611,0.02743973],"study_design_scores_gemma":[0.8436271,0.1495549,0.004511034,0.00002421646,0.0003322861,0.0000434974,0.00003825421,0.000563247,0.0005113319,0.0001485513,0.0006304137,0.00001520036],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950236,0.001580168,0.0003796756,0.0002555988,0.0001565905,0.0008689958,0.0006396766,0.00005261247,0.001043098],"genre_scores_gemma":[0.9896126,0.001883027,0.001625726,0.0005350366,0.0002211098,0.00168722,0.001134687,0.00004570903,0.00325478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00510401,"threshold_uncertainty_score":0.01707458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05815835894789728,"score_gpt":0.3220258166822701,"score_spread":0.2638674577343729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}