{"id":"W2155812602","doi":"10.1016/j.jmb.2010.01.006","title":"The Glycine-Rich Motif of Pyrococcus abyssi DNA Polymerase D Is Critical for Protein Stability","year":2010,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Réseau Provincial de Recherche en Adaptation-Réadaptation; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"DNA polymerase; Polymerase; Mutant; Biochemistry; Thermostability; DNA; Biology; Chemistry; Molecular biology; Enzyme; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002446006,0.0004454612,0.00041184,0.0001658315,0.0003253276,0.0004752444,0.0002966962,0.0006109841,0.0009242781],"category_scores_gemma":[0.0005358311,0.0002709998,0.0002999619,0.0001189535,0.0004355782,0.0003154029,0.0004259946,0.0006044541,0.0008944342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004383499,"about_ca_system_score_gemma":0.0004034206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005119645,"about_ca_topic_score_gemma":0.0004456449,"domain_scores_codex":[0.9998164,0.00003838538,0.00002617643,0.00004822684,0.00004290935,0.00002789045],"domain_scores_gemma":[0.9995576,0.00009051492,0.0001250162,0.00005110812,0.00004266791,0.0001331711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001827482,0.00001516498,0.0006253817,0.00004327216,0.000008564951,0.0002016514,0.00001915048,0.0001565869,0.9974145,0.0001557127,0.0000506758,0.001126648],"study_design_scores_gemma":[0.00004199638,0.000176893,0.006030989,0.00001050055,0.00001408402,0.0008363702,0.00004692905,0.0014319,0.9893582,0.0002258852,0.001811182,0.00001516099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934017,0.0008359542,0.004666288,0.0001543026,0.0000630222,0.00001960883,0.0001477098,0.0001563394,0.0005550091],"genre_scores_gemma":[0.9978577,0.00009083829,0.001494752,0.00005584581,0.00001137895,0.000007240309,0.0001846376,0.00002415419,0.00027335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009242781,"threshold_uncertainty_score":0.003180444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007582142140245699,"score_gpt":0.2776763520124902,"score_spread":0.2700942098722445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}