{"id":"W2155980596","doi":"10.1210/en.2009-0816","title":"Gonadotropin-Releasing Hormone-I-Mediated Activation of Progesterone Receptor Contributes to Gonadotropin α-Subunit Expression in Mouse Gonadotrophs","year":2010,"lang":"en","type":"article","venue":"Endocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Child and Family Research Institute","keywords":"Endocrinology; Internal medicine; Gene knockdown; Gonadotropin-releasing hormone; Gonadotropin; Reporter gene; Gene expression; Biology; Progesterone receptor; G alpha subunit; Gonadotropic cell; Luciferase; Chemistry; Cell culture; Protein subunit; Hormone; Pituitary gland; Luteinizing hormone; Gene; Transfection; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001468135,0.0003674558,0.0009210223,0.0007938518,0.00006973527,0.00001551802,0.0002673815,0.0002607721,0.0001130442],"category_scores_gemma":[0.002127943,0.0003436299,0.0001150935,0.0004826727,0.0002704802,0.0001923419,0.0001731781,0.0009104086,0.0001308852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002068013,"about_ca_system_score_gemma":0.0002158081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002624663,"about_ca_topic_score_gemma":0.00006171268,"domain_scores_codex":[0.9971415,0.0001784395,0.0008057866,0.0007527763,0.0003209691,0.0008005167],"domain_scores_gemma":[0.9980044,0.0002889762,0.0002874641,0.0008163787,0.0004007256,0.0002020351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001670623,0.0004177166,0.02248565,0.00004640759,0.00007469227,0.00003131013,0.00018817,0.00001008765,0.962872,0.000639887,0.0004660549,0.01109746],"study_design_scores_gemma":[0.005140901,0.0006993267,0.4465268,0.0000920623,0.00003293433,0.00007008426,0.000123908,0.00004402521,0.5289136,0.00008943705,0.01800556,0.0002613098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893406,0.000545126,0.000698765,0.007037544,0.0003997895,0.001579165,0.00003882213,0.0001492808,0.0002109199],"genre_scores_gemma":[0.9930156,0.000162982,0.00533506,0.0003162852,0.0002377063,0.0002021163,0.0000957343,0.00006851191,0.000566013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4339583,"threshold_uncertainty_score":0.9999016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286189282013715,"score_gpt":0.2638328871644303,"score_spread":0.2509709943442931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}