{"id":"W2155994411","doi":"10.1177/0267659115583525","title":"Bivalirudin as an adjunctive anticoagulant to heparin in the treatment of heparin resistance during cardiopulmonary bypass-assisted cardiac surgery","year":2015,"lang":"en","type":"review","venue":"Perfusion","topic":"Heparin-Induced Thrombocytopenia and Thrombosis","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Health Authority","funders":"Sandoz; Sandoz Canada","keywords":"Medicine; Bivalirudin; Heparin; Cardiopulmonary bypass; Activated clotting time; Anticoagulant; Anesthesia; Cardiac surgery; Protamine; Direct thrombin inhibitor; Heparin-induced thrombocytopenia; Cardiology; Surgery; Warfarin; Atrial fibrillation; Percutaneous coronary intervention; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001312621,0.0009062096,0.006107454,0.0007635386,0.0001743728,0.00004524194,0.0003927267,0.0005371999,0.00003823622],"category_scores_gemma":[0.0001671699,0.0005883099,0.001327233,0.001356869,0.0001049797,0.000123239,0.000164061,0.000450327,0.0001065511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001463456,"about_ca_system_score_gemma":0.001060956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002903433,"about_ca_topic_score_gemma":0.000541905,"domain_scores_codex":[0.9943932,0.001412547,0.001382664,0.001133599,0.0009560785,0.0007219475],"domain_scores_gemma":[0.9966114,0.0004326847,0.0004511888,0.001821404,0.0002248229,0.000458557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001207726,0.003866436,0.01244086,0.01158867,0.001270974,0.001584366,0.003861908,0.000001743511,0.001321446,0.00008790389,0.00106814,0.9616998],"study_design_scores_gemma":[0.0009254321,0.001048066,0.06678219,0.01598092,0.003630289,0.0002674869,0.0004360584,0.000003341334,0.0004474815,0.00001985671,0.9095185,0.000940392],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4345526,0.5595528,3.274758e-7,0.00009568018,0.0004265918,0.002698465,0.0001317165,0.00005504486,0.002486685],"genre_scores_gemma":[0.1058809,0.8917714,0.00007645038,0.00002924238,0.0003939955,0.0005076214,0.0005885249,0.0001261391,0.000625712],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9607594,"threshold_uncertainty_score":0.9996569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1280950908016724,"score_gpt":0.3841495986897367,"score_spread":0.2560545078880644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}